607 (<15): Beginner CASP10 Refinement Puzzle: TR747

Closed since over 13 years ago

Summary

• Created: July 27, 2012
• Expires: August 04, 2012 at 13:00 UTC
• Max points: 100

Description

This is the seventeenth CASP10 Refinement Target. This model was the best server prediction for target T0747, generated by the Mufold server. We've been told that ~83% of this model matches the native, so you just need to find which 17% to refine! Luckily, this is a short target with only 98 residues. More info in the puzzle comments. For players with fewer than 15 global points.

Top groups

• 1. SETIKAH@KOREA 100 pts. 10,176
• 2. L'Alliance Francophone 4 pts. 10,120
• 3. Deleted group pts. 10,071

Top soloists

• 11. llchlittlelee 64 pts. 10,073
• 12. champuli1 61 pts. 10,071
• 13. AmysCrazy 58 pts. 10,057
• 14. Oa10712 55 pts. 10,054
• 15. zerofayt 53 pts. 10,047
• 16. flip88 50 pts. 10,034
• 17. arlok 48 pts. 10,032
• 18. BigA 45 pts. 10,024
• 19. Neur001 43 pts. 10,020
• 20. fevernova99 41 pts. 10,019

Comments

[beta_helix]

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

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This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=204

Note that the organizers gave us this hint:

"Starting model GDT_TS=83."

GDT_TS=83 essentially means that ONLY 83% of the model superimposes correctly onto the native structure:

en.wikipedia.org

Global distance test

The global distance test (GDT), also written as GDT_TS to represent "total score", is a measure of similarity between two protein structures with known amino acid correspondences (e.g. identical amino acid sequences) but different tertiary structures. It is most commonly used to compare the results of protein structure prediction to the experimentally determined structure as measured by X-ray crystallography, protein NMR, or, increasingly, cryoelectron microscopy. The metric was developed by Ada...