607 (<150): Beginner CASP10 Refinement Puzzle: TR747

Closed since over 13 years ago

Summary

• Created: July 27, 2012
• Expires: August 04, 2012 at 13:00 UTC
• Max points: 100

Description

This is the seventeenth CASP10 Refinement Target. This model was the best server prediction for target T0747, generated by the Mufold server. We've been told that ~83% of this model matches the native, so you just need to find which 17% to refine! Luckily, this is a short target with only 98 residues. More info in the puzzle comments. For players with fewer than 150 global points.

Top groups

• 1. Gargleblasters 100 pts. 10,370
• 2. SETIKAH@KOREA 60 pts. 10,244
• 3. Anthropic Dreams 33 pts. 10,171
• 4. Cannabis Crew 17 pts. 10,170
• 5. Nerdfighters 8 pts. 10,087
• 6. Geekdo 4 pts. 10,042
• 7. Team Canada 2 pts. 9,954
• 8. :) 1 pt. 9,887
• 9. DSN @ Home 1 pt. 9,881
• 10. Team China 1 pt. 9,689

Top soloists

• 11. vasko 50 pts. 10,099
• 12. sqrt 46 pts. 10,092
• 13. fabiobean 43 pts. 10,087
• 14. Tac1 40 pts. 10,083
• 15. jellyarren 37 pts. 10,069
• 16. Whizz 34 pts. 10,060
• 17. Ben G 31 pts. 10,053
• 18. dbuske 29 pts. 10,042
• 19. AadilValconi 26 pts. 10,035
• 20. Valani 24 pts. 10,032

Comments

[beta_helix]

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

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This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=204

Note that the organizers gave us this hint:

"Starting model GDT_TS=83."

GDT_TS=83 essentially means that ONLY 83% of the model superimposes correctly onto the native structure:

en.wikipedia.org

Global distance test

The global distance test (GDT), also written as GDT_TS to represent "total score", is a measure of similarity between two protein structures with known amino acid correspondences (e.g. identical amino acid sequences) but different tertiary structures. It is most commonly used to compare the results of protein structure prediction to the experimentally determined structure as measured by X-ray crystallography, protein NMR, or, increasingly, cryoelectron microscopy. The metric was developed by Ada...