609 (<15): Beginner CASP10 Refinement Puzzle: TR696

Closed since over 13 years ago

Summary

• Created: July 31, 2012
• Expires: August 08, 2012 at 12:00 UTC
• Max points: 100

Description

This is the nineteenth CASP10 Refinement Target. This model was the best server prediction for target T0696, generated by the Bilab-Enable server. We've been told that ~71% of this model matches the native, so you just need to find which 29% to refine! Luckily, this is a short target with only 100 residues. More info in the puzzle comments.

Top groups

• 1. Brony@Home 100 pts. 9,996
• 2. SETIKAH@KOREA 24 pts. 9,767
• 3. Go Science 4 pts. 9,713
• 4. Crunching Family 1 pt. 9,372
• 5. L'Alliance Francophone 1 pt. 9,354

Top soloists

• 31. Casandraelf 25 pts. 9,358
• 32. fla_ 24 pts. 9,354
• 33. kado3646 22 pts. 9,341
• 34. skgiven 21 pts. 9,335
• 35. rarkenin 20 pts. 9,335
• 36. Slek 19 pts. 9,329
• 37. Trev625 18 pts. 9,326
• 38. rpcrittenden 17 pts. 9,322
• 39. pmorawiecki 16 pts. 9,319
• 40. evilgrinners 15 pts. 9,318

Comments

[beta_helix]

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

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This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=196

Note that the organizers gave us this hint:

"Starting model GDT_TS=71."

GDT_TS=71 essentially means that ONLY 71% of the model superimposes correctly onto the native structure:

en.wikipedia.org

Global distance test

The global distance test (GDT), also written as GDT_TS to represent "total score", is a measure of similarity between two protein structures with known amino acid correspondences (e.g. identical amino acid sequences) but different tertiary structures. It is most commonly used to compare the results of protein structure prediction to the experimentally determined structure as measured by X-ray crystallography, protein NMR, or, increasingly, cryoelectron microscopy. The metric was developed by Ada...