Placeholder image of a protein
Icon representing a puzzle

610: CASP10 Refinement Puzzle: TR750

Closed since over 13 years ago

Intermediate Overall Prediction

Summary

Created
August 01, 2012
Expires
Max points
100
Description

This is the twentieth CASP10 Refinement Target. We've been told that ~77% of this model matches the native, so you'll need to refine ~23% of the structure! More info in the puzzle comments.

Top groups

  1. Avatar for Gargleblasters 11. Gargleblasters 5 pts. 12,047
  2. Avatar for HMT heritage 12. HMT heritage 4 pts. 12,043
  3. Avatar for SETI.Germany 13. SETI.Germany 2 pts. 11,670
  4. Avatar for Deleted group 14. Deleted group pts. 11,663
  5. Avatar for Natural Abilities 15. Natural Abilities 1 pt. 11,633
  6. Avatar for Mojo Risin' 16. Mojo Risin' 1 pt. 11,239
  7. Avatar for Brony@Home 17. Brony@Home 1 pt. 11,183
  8. Avatar for Czech National Team 18. Czech National Team 1 pt. 11,031
  9. Avatar for Team Canada 19. Team Canada 1 pt. 10,911
  10. Avatar for DSN @ Home 20. DSN @ Home 1 pt. 10,721
  1. Avatar for Deleted player 71. Deleted player pts. 11,852
  2. Avatar for brow42 72. brow42 Lv 1 12 pts. 11,848
  3. Avatar for goastano 73. goastano Lv 1 12 pts. 11,835
  4. Avatar for GenGF 74. GenGF Lv 1 11 pts. 11,817
  5. Avatar for Grom 75. Grom Lv 1 11 pts. 11,785
  6. Avatar for ErichVonSterich 76. ErichVonSterich Lv 1 11 pts. 11,774
  7. Avatar for barbaranne 77. barbaranne Lv 1 10 pts. 11,751
  8. Avatar for abiogenesis 78. abiogenesis Lv 1 10 pts. 11,748
  9. Avatar for jeff101 79. jeff101 Lv 1 9 pts. 11,740
  10. Avatar for reefyrob 80. reefyrob Lv 1 9 pts. 11,735

Comments

beta_helix Staff Lv 1

Please note that the Cut Tool is available on all puzzles from now on!

This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=202

The CASP10 organizers gave us this hint:

"Starting model GDT_TS=77."

GDT_TS=77 essentially means that 77% of the model superimposes correctly onto the native structure:

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 84 & 176 are highly predicted to be part of a helix. However, the Valines at residues 64-65 & 99 are predicted to be part of a sheet.