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611: CASP10 Refinement Puzzle: TR752

Closed since over 13 years ago

Intermediate Overall Prediction

Summary


Created
August 02, 2012
Expires
Max points
100
Description

This is the twenty-first CASP10 Refinement Target. This model was the best server prediction for target T0752, generated by the BAKER-ROSETTASERVER (using Rosetta@home). We've been told that ~90% of this model matches the native! So (for once) you won't need to change the starting model much. In addition, the organizers have given us "Special attention regions: 41-50, 100-110, 125-128." These are highlighted in Note Mode.

Top groups


  1. Avatar for Natural Abilities 11. Natural Abilities 4 pts. 11,897
  2. Avatar for Russian team 12. Russian team 2 pts. 11,879
  3. Avatar for Gargleblasters 13. Gargleblasters 2 pts. 11,842
  4. Avatar for SETI.Germany 14. SETI.Germany 1 pt. 11,634
  5. Avatar for Deleted group 15. Deleted group pts. 11,629
  6. Avatar for SETIKAH@KOREA 16. SETIKAH@KOREA 1 pt. 11,535
  7. Avatar for Geekdo 17. Geekdo 1 pt. 11,492
  8. Avatar for Mojo Risin' 18. Mojo Risin' 1 pt. 11,422
  9. Avatar for Team Canada 19. Team Canada 1 pt. 11,357
  10. Avatar for 7Monkeys 20. 7Monkeys 1 pt. 11,249

  1. Avatar for rsosborne 41. rsosborne Lv 1 30 pts. 11,943
  2. Avatar for ViJay7019 42. ViJay7019 Lv 1 29 pts. 11,942
  3. Avatar for gramps 43. gramps Lv 1 28 pts. 11,926
  4. Avatar for mottiger 44. mottiger Lv 1 27 pts. 11,923
  5. Avatar for Jajaboman 45. Jajaboman Lv 1 26 pts. 11,912
  6. Avatar for pgiles 46. pgiles Lv 1 25 pts. 11,907
  7. Avatar for mbinfield 47. mbinfield Lv 1 24 pts. 11,902
  8. Avatar for martinzblavy 48. martinzblavy Lv 1 24 pts. 11,899
  9. Avatar for Mr_Jolty 49. Mr_Jolty Lv 1 23 pts. 11,897
  10. Avatar for twisted1 50. twisted1 Lv 1 22 pts. 11,897

Comments


beta_helix Staff Lv 1

Please look at the Notes for this puzzle (by pressing 3 in the Original Interface, or pressing 1 in the Selection Interface).

We recommend focusing your work on these 3 regions.


This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=203

The CASP10 organizers gave us this hint:

"Starting model GDT_TS=90. Special attention regions: 41-50, 100-110, 125-128."

GDT_TS=90 essentially means that 90% of the model superimposes correctly onto the native structure:

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 80-81, 94, 114-115, 123 & 134 are highly predicted to be part of a sheet. However, the Valines at residues 45, 52 & 103 are predicted to be in anything.