Placeholder image of a protein
Icon representing a puzzle

612: Quick CASP10 Refinement Puzzle: TR722

Closed since over 13 years ago

Intermediate Overall Prediction

Summary

Created
August 02, 2012
Expires
Max points
100
Description

As mentioned in Puzzle 608: this Rosetta model was the best server prediction for target T0722, but only ~58% of this model matches the solved structure. We are giving you this model without symmetry, in case it folds up as a monomer. This quick puzzle is worth 70 global points. More info in the puzzle comments.

Top groups

  1. Avatar for Gargleblasters 11. Gargleblasters 3 pts. 10,687
  2. Avatar for HMT heritage 12. HMT heritage 2 pts. 10,654
  3. Avatar for FoldIt@Netherlands 13. FoldIt@Netherlands 1 pt. 10,641
  4. Avatar for Deleted group 14. Deleted group pts. 10,605
  5. Avatar for Piratenpartei Deutschland 15. Piratenpartei Deutschland 1 pt. 10,576
  6. Avatar for Natural Abilities 16. Natural Abilities 1 pt. 10,490
  7. Avatar for DSN @ Home 17. DSN @ Home 1 pt. 10,409
  8. Avatar for Crunching Family 18. Crunching Family 1 pt. 10,406
  9. Avatar for SETIKAH@KOREA 19. SETIKAH@KOREA 1 pt. 10,391
  10. Avatar for Team Canada 20. Team Canada 1 pt. 10,357
  1. Avatar for drjr 91. drjr Lv 1 3 pts. 10,599
  2. Avatar for ege 92. ege Lv 1 2 pts. 10,597
  3. Avatar for phi16 93. phi16 Lv 1 2 pts. 10,595
  4. Avatar for lynnai 94. lynnai Lv 1 2 pts. 10,595
  5. Avatar for splonkify 95. splonkify Lv 1 2 pts. 10,594
  6. Avatar for aendgraend 96. aendgraend Lv 1 2 pts. 10,589
  7. Avatar for twisted1 97. twisted1 Lv 1 2 pts. 10,589
  8. Avatar for Deleted player 98. Deleted player pts. 10,588
  9. Avatar for jermainiac 99. jermainiac Lv 1 2 pts. 10,585
  10. Avatar for RabidNimravid 100. RabidNimravid Lv 1 2 pts. 10,583

Comments

beta_helix Staff Lv 1

This is the page for this CASP10 refinement target:
http://predictioncenter.org/casp10/target.cgi?id=195

Note that the organizers gave us this hint:

"Starting model GDT_TS=58."

GDT_TS=58 essentially means that ONLY 58% of the model superimposes correctly onto the native structure:

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 23, 55, 85, 94, 112 & 115 are highly predicted to be part of a helix. However, the Valine at residue 34 is not predicted to be anything.