Placeholder image of a protein
Icon representing a puzzle

Beginner Puzzle: Streptococcal Protein

Closed since over 13 years ago

Beginner Overall

Summary

Created
August 20, 2012
Expires
Max points
100
Description

The fold of this Streptococcal Protein is trapped in a local minimum. Although it looks good, it is incorrect. This is a short 57-residue protein for new players to try out after completing the Introductory Puzzles. The native is shown as a guide on this puzzle, so try using everything you have learned in the Intro levels to match the native fold.

Top groups

  1. Avatar for ROMANIA Team 51. ROMANIA Team 1 pt. 8,925
  2. Avatar for null pointer exception 52. null pointer exception 1 pt. 8,925
  1. Avatar for Tump 471. Tump Lv 1 1 pt. 8,969
  2. Avatar for silentflute 472. silentflute Lv 1 1 pt. 8,969
  3. Avatar for OstanNick 473. OstanNick Lv 1 1 pt. 8,969
  4. Avatar for emmanuelg 474. emmanuelg Lv 1 1 pt. 8,969
  5. Avatar for Siver 475. Siver Lv 1 1 pt. 8,968
  6. Avatar for Svinfot 476. Svinfot Lv 1 1 pt. 8,966
  7. Avatar for nathematics 477. nathematics Lv 1 1 pt. 8,966
  8. Avatar for johngran 478. johngran Lv 1 1 pt. 8,965
  9. Avatar for Cullenknight 479. Cullenknight Lv 1 1 pt. 8,965
  10. Avatar for avatar24972 480. avatar24972 Lv 1 1 pt. 8,964

Comments

beta_helix Staff Lv 1

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide