Placeholder image of a protein
Icon representing a puzzle

Beginner Puzzle (<15): Streptococcal Protein

Closed since over 13 years ago

Beginner Beginner

Summary

Created
August 20, 2012
Expires
Max points
100
Description

The fold of this Streptococcal Protein is trapped in a local minimum. Although it looks good, it is incorrect. This is a short 57-residue protein for new players to try out after completing the Introductory Puzzles. The native is shown as a guide on this puzzle, so try using everything you have learned in the Intro levels to match the native fold. For players with fewer than 15 global points.

Top groups

  1. Avatar for GENE 433
    1. GENE 433
    100 pts. 9,492
  2. Avatar for Russian team 2. Russian team 84 pts. 9,480
  3. Avatar for L'Alliance Francophone 3. L'Alliance Francophone 70 pts. 9,439
  4. Avatar for Gargleblasters 4. Gargleblasters 58 pts. 9,408
  5. Avatar for Richard Dawkins Foundation 5. Richard Dawkins Foundation 48 pts. 9,393
  6. Avatar for Curtin Crowd 6. Curtin Crowd 39 pts. 9,387
  7. Avatar for Anthropic Dreams 7. Anthropic Dreams 32 pts. 9,324
  8. Avatar for Deleted group 8. Deleted group pts. 9,263
  9. Avatar for Deleted group 9. Deleted group pts. 9,242
  10. Avatar for Go Science 10. Go Science 16 pts. 9,218
  1. Avatar for albertoeda 1021. albertoeda Lv 1 2 pts. 8,954
  2. Avatar for Spitinthacoola 1022. Spitinthacoola Lv 1 2 pts. 8,954
  3. Avatar for tigertinite 1023. tigertinite Lv 1 2 pts. 8,954
  4. Avatar for mgorz1 1024. mgorz1 Lv 1 2 pts. 8,954
  5. Avatar for sepro 1025. sepro Lv 1 2 pts. 8,953
  6. Avatar for ghancoc1 1026. ghancoc1 Lv 1 2 pts. 8,953
  7. Avatar for BuddenD 1027. BuddenD Lv 1 2 pts. 8,953
  8. Avatar for psmyth@guidewire.com 1028. psmyth@guidewire.com Lv 1 2 pts. 8,953
  9. Avatar for anok 1029. anok Lv 1 2 pts. 8,953
  10. Avatar for bobbobsonsen 1030. bobbobsonsen Lv 1 2 pts. 8,953

Comments

beta_helix Staff Lv 1

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide