Placeholder image of a protein
Icon representing a puzzle

631: Electron Density Puzzle 10

Closed since over 13 years ago

Intermediate Overall Prediction Electron Density

Summary

Created
September 19, 2012
Expires
Max points
100
Description

In this electron density puzzle, we're starting you with an extended chain. You'll have to use the electron density as a guide in order to find the correct fold. Try to find the best fit for the protein inside of the guide, while still maintaining a good fold. We have posted the secondary structure predictions in the puzzle comments and put them on the starting extended chain. Get started by completing the electron density intro level (5-3).

Top groups

  1. Avatar for foldeRNA 11. foldeRNA 18 pts. 10,561
  2. Avatar for HMT heritage 12. HMT heritage 15 pts. 10,449
  3. Avatar for Natural Abilities 13. Natural Abilities 12 pts. 10,382
  4. Avatar for Friday Lab 14. Friday Lab 9 pts. 10,368
  5. Avatar for FoldIt@Netherlands 15. FoldIt@Netherlands 8 pts. 10,182
  6. Avatar for Richard Dawkins Foundation 16. Richard Dawkins Foundation 6 pts. 9,538
  7. Avatar for Nerdfighters 17. Nerdfighters 5 pts. 9,487
  8. Avatar for Russian team 18. Russian team 4 pts. 9,384
  9. Avatar for Brony@Home 19. Brony@Home 3 pts. 9,260
  10. Avatar for Geekdo 20. Geekdo 2 pts. 9,163
  1. Avatar for karstenw
    1. karstenw Lv 1
    100 pts. 12,140
  2. Avatar for steveB 2. steveB Lv 1 99 pts. 12,027
  3. Avatar for Susume 3. Susume Lv 1 97 pts. 12,021
  4. Avatar for utaca 4. utaca Lv 1 96 pts. 11,921
  5. Avatar for malthreSC 5. malthreSC Lv 1 94 pts. 11,837
  6. Avatar for mimi 6. mimi Lv 1 93 pts. 11,559
  7. Avatar for brow42 7. brow42 Lv 1 92 pts. 11,545
  8. Avatar for Timo van der Laan 8. Timo van der Laan Lv 1 90 pts. 11,047
  9. Avatar for Bautho 9. Bautho Lv 1 89 pts. 10,985
  10. Avatar for smilingone 10. smilingone Lv 1 87 pts. 10,985

Comments

beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 7 & 68 are highly predicted to be part of a helix. However, the Valines at residues 31, 35, 43, 52, 88, 97, 101 & 120 are highly predicted to be in a sheet.