635: De-novo Freestyle 15

Closed since over 13 years ago

Summary

• Created: September 27, 2012
• Expires: October 06, 2012 at 19:00 UTC
• Max points: 100

Description

This currently unsolved protein does not have any templates that we can use, so we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, and included in the starting structure as well.

Top groups

• 11. Deleted group pts. 10,311
• 12. Gargleblasters 21 pts. 10,308
• 13. Richard Dawkins Foundation 17 pts. 10,223
• 14. SETI.Germany 15 pts. 10,209
• 15. Russian team 12 pts. 10,206
• 16. FoldIt@Netherlands 10 pts. 10,134
• 17. Deleted group pts. 10,104
• 18. Friday Lab 7 pts. 10,045
• 19. Nerdfighters 6 pts. 10,008
• 20. Deleted group pts. 10,002

Top soloists

• 1. stg123123 100 pts. 10,779
• 2. marie_s 99 pts. 10,752
• 3. steveB 98 pts. 10,734
• 4. Timo van der Laan 97 pts. 10,720
• 5. doug.ehlert 95 pts. 10,717
• 6. mimi 94 pts. 10,715
• 7. jakbinimbol 93 pts. 10,688
• 8. yoyo washington 92 pts. 10,682
• 9. utaca 90 pts. 10,676
• 10. smilingone 89 pts. 10,671

Comments

[beta_helix]

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 16, 54 & 110 are highly predicted to be part of a sheet. However, the Valine at residue 89 is predicted to be in a loop!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).