635: De-novo Freestyle 15

Closed since over 13 years ago

Summary

• Created: September 27, 2012
• Expires: October 06, 2012 at 19:00 UTC
• Max points: 100

Description

This currently unsolved protein does not have any templates that we can use, so we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, and included in the starting structure as well.

Top groups

• 31. Geekdo 1 pt. 8,825
• 32. Atheists, Skeptics, & Humanists 1 pt. 8,709
• 33. Czech National Team 1 pt. 8,590
• 34. DSN @ Home 1 pt. 8,502
• 35. Rice Biochemistry 1 pt. 8,428
• 36. SETIKAH@KOREA 1 pt. 8,119
• 37. null pointer exception 1 pt. 7,677
• 38. Skeptics Guide to the Universe 1 pt. 7,677
• 39. SOAR High School Biology 1 pt. 7,584
• 40. Cannabis Crew 1 pt. 6,628

Top soloists

• 111. FlingeR 18 pts. 10,012
• 112. Close At Hand 18 pts. 10,011
• 113. Jobriq 18 pts. 10,008
• 114. Deleted player pts. 10,002
• 115. tscherulli 17 pts. 9,993
• 116. anne romaine 17 pts. 9,980
• 117. truestone 16 pts. 9,971
• 118. weurhartdezirez 16 pts. 9,962
• 119. jobo0502 16 pts. 9,953
• 120. frostschutz 15 pts. 9,947

Comments

[beta_helix]

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 16, 54 & 110 are highly predicted to be part of a sheet. However, the Valine at residue 89 is predicted to be in a loop!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).