635: De-novo Freestyle 15

Closed since over 13 years ago

Summary

• Created: September 27, 2012
• Expires: October 06, 2012 at 19:00 UTC
• Max points: 100

Description

This currently unsolved protein does not have any templates that we can use, so we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, and included in the starting structure as well.

Top groups

• 41. test_group1 1 pt. 6,282

Top evolvers

• 1. smilingone 100 pts. 10,776
• 2. Deleted player 88 pts. 10,776
• 3. Dolichwier 77 pts. 10,736
• 4. utaca 68 pts. 10,720
• 5. Bletchley Park 59 pts. 10,704
• 6. mimi 51 pts. 10,692
• 7. martinzblavy 44 pts. 10,691
• 8. gitwut 38 pts. 10,691
• 9. Galaxie 32 pts. 10,676
• 10. gmn 27 pts. 10,675

Comments

[beta_helix]

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 16, 54 & 110 are highly predicted to be part of a sheet. However, the Valine at residue 89 is predicted to be in a loop!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).