Foldit

635: De-novo Freestyle 15

Closed since over 13 years ago

Summary

Created: September 27, 2012
Expires: October 06, 2012 at 19:00 UTC
Max points: 100

Description

This currently unsolved protein does not have any templates that we can use, so we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, and included in the starting structure as well.

Top groups

1. Beta Folders
100 pts. 10,779
2. Void Crushers 89 pts. 10,736
3. Contenders 78 pts. 10,717
4. L'Alliance Francophone 68 pts. 10,682
5. Anthropic Dreams 60 pts. 10,676
6. foldeRNA 52 pts. 10,564
7. Go Science 45 pts. 10,545
8. HMT heritage 39 pts. 10,422
9. putting the eat in meat 33 pts. 10,398
10. Foldit UK 28 pts. 10,378

31. histon Lv 1 1 pt. 10,422
32. montadar Lv 1 1 pt. 10,308
33. truestone Lv 1 1 pt. 10,294
34. PaladinOne Lv 1 1 pt. 10,294
35. C_M Lv 1 1 pt. 10,219
36. JasperD Lv 1 1 pt. 10,190
37. lynnai Lv 1 1 pt. 10,180
38. micheldeweerd Lv 1 1 pt. 10,139
39. Dixie2 Lv 1 1 pt. 10,134
40. harvardman Lv 1 1 pt. 9,475

Comments

beta_helix Staff Lv 1

September 27, 2012

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 16, 54 & 110 are highly predicted to be part of a sheet. However, the Valine at residue 89 is predicted to be in a loop!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).