Placeholder image of a protein
Icon representing a puzzle

635: De-novo Freestyle 15

Closed since over 13 years ago

Advanced Overall Prediction

Summary


Created
September 27, 2012
Expires
Max points
100
Description

This currently unsolved protein does not have any templates that we can use, so we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, and included in the starting structure as well.

Top groups


  1. Avatar for Beta Folders 100 pts. 10,779
  2. Avatar for Void Crushers 2. Void Crushers 89 pts. 10,736
  3. Avatar for Contenders 3. Contenders 78 pts. 10,717
  4. Avatar for L'Alliance Francophone 4. L'Alliance Francophone 68 pts. 10,682
  5. Avatar for Anthropic Dreams 5. Anthropic Dreams 60 pts. 10,676
  6. Avatar for foldeRNA 6. foldeRNA 52 pts. 10,564
  7. Avatar for Go Science 7. Go Science 45 pts. 10,545
  8. Avatar for HMT heritage 8. HMT heritage 39 pts. 10,422
  9. Avatar for putting the eat in meat 9. putting the eat in meat 33 pts. 10,398
  10. Avatar for Foldit UK 10. Foldit UK 28 pts. 10,378

  1. Avatar for telesphore4 31. telesphore4 Lv 1 66 pts. 10,470
  2. Avatar for grogar7 32. grogar7 Lv 1 66 pts. 10,467
  3. Avatar for drjr 33. drjr Lv 1 65 pts. 10,454
  4. Avatar for mirp 34. mirp Lv 1 64 pts. 10,446
  5. Avatar for johnmitch 35. johnmitch Lv 1 63 pts. 10,429
  6. Avatar for Rav3n_pl 36. Rav3n_pl Lv 1 62 pts. 10,425
  7. Avatar for jermainiac 37. jermainiac Lv 1 61 pts. 10,419
  8. Avatar for enszyme 38. enszyme Lv 1 60 pts. 10,418
  9. Avatar for Aubade00 39. Aubade00 Lv 1 59 pts. 10,417
  10. Avatar for O Seki To 40. O Seki To Lv 1 58 pts. 10,414

Comments


beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 16, 54 & 110 are highly predicted to be part of a sheet. However, the Valine at residue 89 is predicted to be in a loop!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).