637: De-novo Freestyle 16

Closed since over 13 years ago

Summary

• Created: October 04, 2012
• Expires: October 10, 2012 at 23:59 UTC
• Max points: 100

Description

This currently unsolved short protein does not have any templates that we can use, so we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments.

Top groups

• 21. Friday Lab 1 pt. 9,127
• 22. GENE 433 1 pt. 9,101
• 23. Eὕρηκα! Heureka! 1 pt. 9,089
• 24. CHNO Junkies 1 pt. 9,042
• 25. Androids 1 pt. 8,825
• 26. Atheists, Skeptics, & Humanists 1 pt. 8,793
• 27. Curtin Crowd 1 pt. 8,577
• 28. Rice Biochemistry 1 pt. 8,254

Top soloists

• 11. auntdeen 85 pts. 9,673
• 12. djag 84 pts. 9,660
• 13. SimplySue 82 pts. 9,653
• 14. meatexplosion 81 pts. 9,650
• 15. steveB 80 pts. 9,648
• 16. smilingone 78 pts. 9,641
• 17. jamiexq 77 pts. 9,637
• 18. jakbinimbol 76 pts. 9,628
• 19. christioanchauvin 74 pts. 9,623
• 20. marie_s 73 pts. 9,621

Comments

[beta_helix]

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 20 & 45 are highly predicted to be part of a sheet. However, the Valine at residue 2 is not predicted to be anything!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).

[spmm]

this has a pivot around 36-43