Placeholder image of a protein
Icon representing a puzzle

641: CASP ROLL Target R0020

Closed since over 13 years ago

Intermediate Overall Prediction CASP ROLL

Summary


Created
October 11, 2012
Expires
Max points
100
Description

CASP ROLL is back! We are providing you with 3 templates for now (in hope that one of them is correct), and will give you with some server predictions once they are released. More details about this CASP target are in the puzzle comments.

Top groups


  1. Avatar for BOINC@Poland 11. BOINC@Poland 18 pts. 10,322
  2. Avatar for Richard Dawkins Foundation 12. Richard Dawkins Foundation 15 pts. 10,209
  3. Avatar for Brony@Home 13. Brony@Home 12 pts. 10,199
  4. Avatar for putting the eat in meat 14. putting the eat in meat 9 pts. 10,177
  5. Avatar for Curtin Crowd 15. Curtin Crowd 8 pts. 10,137
  6. Avatar for Russian team 16. Russian team 6 pts. 10,111
  7. Avatar for Foldit UK 17. Foldit UK 5 pts. 10,083
  8. Avatar for SETI.Germany 18. SETI.Germany 4 pts. 10,048
  9. Avatar for FoldIt@Netherlands 19. FoldIt@Netherlands 3 pts. 10,008
  10. Avatar for Deleted group 20. Deleted group pts. 9,971

  1. Avatar for goastano 51. goastano Lv 1 44 pts. 10,383
  2. Avatar for christioanchauvin 52. christioanchauvin Lv 1 43 pts. 10,371
  3. Avatar for Jim Fraser 53. Jim Fraser Lv 1 42 pts. 10,361
  4. Avatar for JasperD 54. JasperD Lv 1 42 pts. 10,350
  5. Avatar for truestone 55. truestone Lv 1 41 pts. 10,350
  6. Avatar for SKSbell 56. SKSbell Lv 1 40 pts. 10,337
  7. Avatar for gramps 57. gramps Lv 1 39 pts. 10,333
  8. Avatar for drumpeter18yrs9yrs 58. drumpeter18yrs9yrs Lv 1 39 pts. 10,330
  9. Avatar for keithv 59. keithv Lv 1 38 pts. 10,324
  10. Avatar for faron4 60. faron4 Lv 1 37 pts. 10,322

Comments


beta_helix Staff Lv 1

Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casproll/target.cgi?id=63

You'll notice that the sequence we have given you has been trimmed (compared to the one on the CASP ROLL website). This is because the N-terminus is predicted to be a signal peptide by the Rosetta Server:
http://rosettaserver.bakerlab.org/results.jsp?id=34040

For more info on that: http://en.wikipedia.org/wiki/Signal_peptide
__________________

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 16, 54 & 110 are highly predicted to be part of a sheet. However, the Valine at residue 89 is predicted to be in a loop!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).
__________________

Link to template PDBs:

http://www.pdb.org/pdb/explore/explore.do?structureId=3iuu
http://www.pdb.org/pdb/explore/explore.do?structureId=2jvf
http://www.pdb.org/pdb/explore/explore.do?structureId=1qys