Placeholder image of a protein
Icon representing a puzzle

641: CASP ROLL Target R0020

Closed since over 13 years ago

Intermediate Overall Prediction CASP ROLL

Summary


Created
October 11, 2012
Expires
Max points
100
Description

CASP ROLL is back! We are providing you with 3 templates for now (in hope that one of them is correct), and will give you with some server predictions once they are released. More details about this CASP target are in the puzzle comments.

Top groups


  1. Avatar for L'Alliance Francophone 100 pts. 10,866
  2. Avatar for Void Crushers 2. Void Crushers 87 pts. 10,859
  3. Avatar for Anthropic Dreams 3. Anthropic Dreams 74 pts. 10,857
  4. Avatar for Contenders 4. Contenders 64 pts. 10,827
  5. Avatar for Go Science 5. Go Science 54 pts. 10,659
  6. Avatar for foldeRNA 6. foldeRNA 46 pts. 10,634
  7. Avatar for Beta Folders 7. Beta Folders 38 pts. 10,630
  8. Avatar for Deleted group 8. Deleted group pts. 10,555
  9. Avatar for Gargleblasters 9. Gargleblasters 27 pts. 10,387
  10. Avatar for Deleted group 10. Deleted group pts. 10,330

  1. Avatar for SOARcdur 281. SOARcdur Lv 1 1 pt. 7,677
  2. Avatar for crawlee34225 282. crawlee34225 Lv 1 1 pt. 7,677
  3. Avatar for birdy_ssr 283. birdy_ssr Lv 1 1 pt. 7,677
  4. Avatar for Greg60 284. Greg60 Lv 1 1 pt. 7,677
  5. Avatar for HououinKyouma 285. HououinKyouma Lv 1 1 pt. 7,676
  6. Avatar for minimejosh 286. minimejosh Lv 1 1 pt. 7,676
  7. Avatar for spirogyra 287. spirogyra Lv 1 1 pt. 7,676
  8. Avatar for Helix Newton 288. Helix Newton Lv 1 1 pt. 7,676
  9. Avatar for nexpl 289. nexpl Lv 1 1 pt. 7,676
  10. Avatar for sarahsukin 290. sarahsukin Lv 1 1 pt. 7,676

Comments


beta_helix Staff Lv 1

Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casproll/target.cgi?id=63

You'll notice that the sequence we have given you has been trimmed (compared to the one on the CASP ROLL website). This is because the N-terminus is predicted to be a signal peptide by the Rosetta Server:
http://rosettaserver.bakerlab.org/results.jsp?id=34040

For more info on that: http://en.wikipedia.org/wiki/Signal_peptide
__________________

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 16, 54 & 110 are highly predicted to be part of a sheet. However, the Valine at residue 89 is predicted to be in a loop!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).
__________________

Link to template PDBs:

http://www.pdb.org/pdb/explore/explore.do?structureId=3iuu
http://www.pdb.org/pdb/explore/explore.do?structureId=2jvf
http://www.pdb.org/pdb/explore/explore.do?structureId=1qys