Placeholder image of a protein
Icon representing a puzzle

643: CASP ROLL Target R0021

Closed since over 13 years ago

Intermediate Overall Prediction CASP ROLL

Summary


Created
October 15, 2012
Expires
Max points
100
Description

Here is the next CASP ROLL target. We are again providing you with 3 templates for now, and will give you with some server predictions once they are released. More details about this CASP target are in the puzzle comments.

Top groups


  1. Avatar for WHAT!!!! 31. WHAT!!!! 1 pt. 6,747
  2. Avatar for HMT heritage 32. HMT heritage 1 pt. 0

  1. Avatar for foldthestuffman 121. foldthestuffman Lv 1 8 pts. 9,640
  2. Avatar for vaifrax 122. vaifrax Lv 1 7 pts. 9,631
  3. Avatar for jobo0502 123. jobo0502 Lv 1 7 pts. 9,623
  4. Avatar for tscherulli 124. tscherulli Lv 1 7 pts. 9,609
  5. Avatar for aendgraend 125. aendgraend Lv 1 7 pts. 9,585
  6. Avatar for MEFreed 126. MEFreed Lv 1 7 pts. 9,577
  7. Avatar for hkilik 127. hkilik Lv 1 6 pts. 9,575
  8. Avatar for Gene 433 128. Gene 433 Lv 1 6 pts. 9,574
  9. Avatar for grogar7 129. grogar7 Lv 1 6 pts. 9,563
  10. Avatar for Origami314 130. Origami314 Lv 1 6 pts. 9,560

Comments


beta_helix Staff Lv 1

Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casproll/target.cgi?id=64

You'll notice that the sequence we have given you has been trimmed (compared to the one on the CASP ROLL website). This is because the N-terminus is predicted to be a signal peptide by the Rosetta Server:
http://rosettaserver.bakerlab.org/results.jsp?id=34067

For more info on that: http://en.wikipedia.org/wiki/Signal_peptide
__________________

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 1, 42 & 83 are highly predicted to be part of a sheet. However, the Valines at residues 9, 10 & 100 are not predicted to be anything!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).
__________________

Link to template PDBs:

http://www.pdb.org/pdb/explore/explore.do?structureId=3dxe http://www.pdb.org/pdb/explore/explore.do?structureId=2jgb http://www.pdb.org/pdb/explore/explore.do?structureId=3na2