651: Electron Density for CASP10 Target T0691 Round 2

Closed since over 13 years ago

Summary

• Created: November 10, 2012
• Expires: November 17, 2012 at 23:00 UTC
• Max points: 100

Description

This is the second round of the density version of the CASP10 target T0691. This time, we've given you server models as starting points, and the density has been updated. The density in the last puzzle was being cut off at the wrong spot along one of the dimensions, and this time around, the density should contain one whole copy of the protein (it's in there somewhere!). Keep in mind that there are some pieces of density from other copies of the protein, and you'll have to figure out which parts actually belong. We're working on some exciting new tools that will allow you to edit which parts of the density you actually see, so stay tuned to the Developer Preview!

Top groups

• 11. Brony@Home 8 pts. 2,282
• 12. Socially Awkward Nerds 6 pts. 2,254
• 13. SETI.Germany 4 pts. 2,010
• 14. FoldIt@Netherlands 3 pts. 2,006
• 15. Origami 2 2 pts. 1,766
• 16. Mojo Risin' 2 pts. 1,744
• 17. Russian team 1 pt. 1,634
• 18. xkcd 1 pt. 1,583
• 19. Natural Abilities 1 pt. 1,527
• 20. Freedom Folders 1 pt. 1,024

Top soloists

• 1. doug.ehlert 100 pts. 3,171
• 2. Aubade00 99 pts. 3,089
• 3. Bletchley Park 97 pts. 2,996
• 4. karstenw 96 pts. 2,933
• 5. gramps 94 pts. 2,931
• 6. auntdeen 93 pts. 2,927
• 7. harp 91 pts. 2,882
• 8. Jim Fraser 90 pts. 2,863
• 9. martinzblavy 88 pts. 2,841
• 10. gmn 87 pts. 2,814

Comments

[Timo van der Laan]

And how about the comment from someone that this one is really a dimer?

[marie_s]

see here
http://predictioncenter.org/casp10/targetlist.cgi
here
http://foldit.wikia.com/wiki/Puzzle_647
here
http://foldit.wikia.com/wiki/Puzzle_572
and here
http://de.foldit.wikia.com/wiki/CASP10

and in the chat a few times.

[jflat06]

Sorry about the numbering issue. This protein is actually a tetramer, not a dimer.

[Bletchley Park]

Would you please tell us which 'TMPL' from the threading window is which quark or zhang model from 'reset puzzle' ? And also which one is thus missing from the cycling of the 'reset puzzle'. It would save us a lot of time in figuring that out.

[Bletchley Park]

I just realized TMPL7 is the straight backbone template. question answered, thank you.

[Susume]

Do we know whether the proteins in the ED are arranged as a tetramer, or whether all the monomers face the same way? Do we know whether the ED includes the long leading helix (segments 1-27) which is missing from the published native?

I ask not just in reference to this puzzle, but in general if a protein is a polymer, will the ED have the proteins arranged into that polymer?