Placeholder image of a protein
Icon representing a puzzle

664 (<150): Unlocked Frizzled Design Puzzle

Closed since about 13 years ago

Beginner Beginner

Summary

Created
December 29, 2012
Expires
Max points
100
Description

This is a the same protein as Puzzle 640 (Frizzled with a wider pocket than Puzzle 659) but this time the helix is unlocked. You can mutate any residue on the helix but none on Frizzled. We still have the new "Residue Interaction Energy" filter. Natural proteins avoid putting Tryptophan, Phenylalanine, and Tyrosine on the surface. However, Foldit often gives a score bonus if you load up the surface of your design with Tryptophan. The ResidueIE filter helps to counteract that, helping you make more useful designs. More details in the puzzle comments. For players with fewer than 150 global points.

Top groups

  1. Avatar for DNA Masters 11. DNA Masters 4 pts. 10,115
  2. Avatar for Nerdfighters 12. Nerdfighters 3 pts. 10,106
  3. Avatar for Skeptics Guide to the Universe 13. Skeptics Guide to the Universe 2 pts. 10,105
  4. Avatar for DSN @ Home 14. DSN @ Home 1 pt. 10,094
  5. Avatar for Bad Monkey 15. Bad Monkey 1 pt. 10,090
  6. Avatar for Deleted group 16. Deleted group pts. 10,085
  7. Avatar for Czech National Team 17. Czech National Team 1 pt. 10,074
  8. Avatar for Anthropic Dreams 18. Anthropic Dreams 1 pt. 10,056
  9. Avatar for GENE 433 19. GENE 433 1 pt. 9,979
  10. Avatar for Window Group 20. Window Group 1 pt. 9,710
  1. Avatar for imcontributingtoscience 71. imcontributingtoscience Lv 1 4 pts. 10,100
  2. Avatar for pushnfall 72. pushnfall Lv 1 3 pts. 10,098
  3. Avatar for elengul 73. elengul Lv 1 3 pts. 10,098
  4. Avatar for alexwaters 74. alexwaters Lv 1 3 pts. 10,096
  5. Avatar for MihoK 75. MihoK Lv 1 3 pts. 10,095
  6. Avatar for aspadistra 76. aspadistra Lv 1 3 pts. 10,094
  7. Avatar for HC815372 77. HC815372 Lv 1 2 pts. 10,094
  8. Avatar for nickbobbitt2015 78. nickbobbitt2015 Lv 1 2 pts. 10,093
  9. Avatar for deans 79. deans Lv 1 2 pts. 10,093
  10. Avatar for Frank Twilleager 80. Frank Twilleager Lv 1 2 pts. 10,093

Comments