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669: De-novo Freestyle 18

Closed since about 13 years ago

Advanced Overall Prediction

Summary

Created
January 14, 2013
Expires
Max points
100
Description

We are giving you this currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

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Comments

beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 38, 63, 111 & 116 are highly predicted to be part of a sheet. However, the Valines at residues 87 & 142 are not predicted to be anything!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).