671: De-novo Freestyle 19

Closed since about 13 years ago

Summary

• Created: January 22, 2013
• Expires: February 01, 2013 at 17:00 UTC
• Max points: 100

Description

We are giving you another currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

Top groups

• 11. foldeRNA 11 pts. 9,624
• 12. Beta Folders 9 pts. 9,600
• 13. SETI.Germany 7 pts. 9,593
• 14. Gargleblasters 5 pts. 9,533
• 15. Richard Dawkins Foundation 4 pts. 9,479
• 16. Androids 3 pts. 9,454
• 17. Team Schleswig-Holstein 2 pts. 9,365
• 18. Aviation High School 1 pt. 9,248
• 19. Natural Abilities 1 pt. 9,242
• 20. Eὕρηκα! Heureka! 1 pt. 9,035

Top evolvers

• 1. Hanto_FZ140E_4G 100 pts. 9,818
• 2. Galaxie 90 pts. 9,800
• 3. jamiexq 81 pts. 9,800
• 4. MurloW 72 pts. 9,799
• 5. wisky 65 pts. 9,791
• 6. auntdeen 57 pts. 9,784
• 7. Bletchley Park 51 pts. 9,775
• 8. BootsMcGraw 45 pts. 9,774
• 9. gitwut 40 pts. 9,774
• 10. mimi 35 pts. 9,773

Comments

[beta_helix]

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 52 & 55 are highly predicted to be part of a helix. However, the Alanines at residues 35, 68 & 71 are not predicted to be anything!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).