Foldit

671: De-novo Freestyle 19

Closed since about 13 years ago

Summary

Created: January 22, 2013
Expires: February 01, 2013 at 17:00 UTC
Max points: 100

Description

We are giving you another currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

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Comments

beta_helix Staff Lv 1

January 22, 2013

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 52 & 55 are highly predicted to be part of a helix. However, the Alanines at residues 35, 68 & 71 are not predicted to be anything!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).