Placeholder image of a protein
Icon representing a puzzle

679: De-novo Freestyle 20

Closed since about 13 years ago

Advanced

Summary

Created
February 18, 2013
Expires
Max points
100
Description

This puzzle had incorrect secondary structure predictions and was replaced by 679b: http://fold.it/portal/node/994551

Top groups

  1. Avatar for L'Alliance Francophone
    1. L'Alliance Francophone
    100 pts. 10,281
  2. Avatar for Anthropic Dreams 2. Anthropic Dreams 77 pts. 10,248
  3. Avatar for Go Science 3. Go Science 58 pts. 10,219
  4. Avatar for Void Crushers 4. Void Crushers 43 pts. 10,035
  5. Avatar for Contenders 5. Contenders 31 pts. 10,030
  6. Avatar for Deleted group 6. Deleted group pts. 10,022
  7. Avatar for Gargleblasters 7. Gargleblasters 15 pts. 9,979
  8. Avatar for foldeRNA 8. foldeRNA 11 pts. 9,950
  9. Avatar for Beta Folders 9. Beta Folders 7 pts. 9,921
  10. Avatar for Richard Dawkins Foundation 10. Richard Dawkins Foundation 5 pts. 9,815
  1. Avatar for christioanchauvin 41. christioanchauvin Lv 1 19 pts. 9,681
  2. Avatar for pgiles 42. pgiles Lv 1 18 pts. 9,676
  3. Avatar for froggs554 43. froggs554 Lv 1 17 pts. 9,642
  4. Avatar for drumpeter18yrs9yrs 44. drumpeter18yrs9yrs Lv 1 16 pts. 9,623
  5. Avatar for aendgraend 45. aendgraend Lv 1 16 pts. 9,605
  6. Avatar for boondog 46. boondog Lv 1 15 pts. 9,602
  7. Avatar for andrewxc 47. andrewxc Lv 1 14 pts. 9,590
  8. Avatar for yoyo washington 48. yoyo washington Lv 1 13 pts. 9,587
  9. Avatar for JackONeill12 49. JackONeill12 Lv 1 13 pts. 9,576
  10. Avatar for Grom 50. Grom Lv 1 12 pts. 9,569

Comments

beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valine at residue 7 is highly predicted to be part of a helix. However, the Valines at residues 61, 73 & 86 are predicted to be part of a sheet!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).

brow42 Lv 1

The structure prediction starts with QEIPAG and ends with QIRIDKINE. However, the first 3 segments and last 4 segments have been removed from the puzzle. This means the structure prediction is off by 3. I'm sure there will be recipes posted shortly that will reapply the correct predictions. Thanks to drumpeter and frood for noticing.