Placeholder image of a protein
Icon representing a puzzle

679b: De-novo Freestyle 20

Closed since about 13 years ago

Advanced Overall Prediction

Summary


Created
February 19, 2013
Expires
Max points
100
Description

We are giving you another currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments. This is a repost of Puzzle 679, you will be able to load in your manual saves from the previous version.

Top groups


  1. Avatar for Eὕρηκα! Heureka! 22. Eὕρηκα! Heureka! 1 pt. 9,039
  2. Avatar for Deleted group 24. Deleted group pts. 8,854
  3. Avatar for Mojo Risin' 25. Mojo Risin' 1 pt. 8,806
  4. Avatar for DNA Masters 27. DNA Masters 1 pt. 7,683
  5. Avatar for Nerdfighters 28. Nerdfighters 1 pt. 7,604
  6. Avatar for DSN @ Home 29. DSN @ Home 1 pt. 7,136

  1. Avatar for GDC322 261. GDC322 Lv 1 1 pt. 7,684
  2. Avatar for earth8845 262. earth8845 Lv 1 1 pt. 7,683
  3. Avatar for Alex333 263. Alex333 Lv 1 1 pt. 7,683
  4. Avatar for abstandsgruen 264. abstandsgruen Lv 1 1 pt. 7,682
  5. Avatar for DanerLex 265. DanerLex Lv 1 1 pt. 7,682
  6. Avatar for Hell_Kitty 266. Hell_Kitty Lv 1 1 pt. 7,680
  7. Avatar for ajbro24 267. ajbro24 Lv 1 1 pt. 7,638
  8. Avatar for Robaa 268. Robaa Lv 1 1 pt. 7,608
  9. Avatar for Quixoticowl 269. Quixoticowl Lv 1 1 pt. 7,604
  10. Avatar for narono 270. narono Lv 1 1 pt. 7,593

Comments


beta_helix Staff Lv 1

Here is the CORRECT sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 58, 70 & 83 are predicted to be part of a sheet, but the Valine at residue 90 is not.

The above predictions are already on the starting model (based on the horizontal lines in the above figure).
______________

NOTE: If you did not manually save a solution in puzzle 679, you can go back to 679, manually save it, and the solution should appear in your manual saves for this puzzle.

Puzzle was reposted due to this bug: http://fold.it/portal/node/994549

beta_helix Staff Lv 1

Due to the above bug (requiring this repost of the puzzle) and the fact that the other current puzzles are quite large (but the CASP ROLL puzzle deadlines cannot be extended) we have extended this puzzle's deadline.