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689: (Old) Hand-Folding CASP10 T0711 Repost

Closed since almost 13 years ago

Intermediate

Summary

Created
March 20, 2013
Expires
Max points
100
Description

This puzzle has been reposted. Please use the new version of this puzzle, 689b. You may load your MANUAL saves into the new puzzle. We apologize for any inconvenience.

Top groups

  1. Avatar for Russian team 11. Russian team 2 pts. 8,261
  2. Avatar for Brony@Home 12. Brony@Home 1 pt. 8,260
  3. Avatar for Beta Folders 13. Beta Folders 1 pt. 8,198
  4. Avatar for 7Monkeys 14. 7Monkeys 1 pt. 8,186
  5. Avatar for Gargleblasters 15. Gargleblasters 1 pt. 8,178
  6. Avatar for Team Schleswig-Holstein 16. Team Schleswig-Holstein 1 pt. 8,139
  7. Avatar for DSN @ Home 17. DSN @ Home 1 pt. 7,979
  8. Avatar for HMT heritage 18. HMT heritage 1 pt. 4,699
  1. Avatar for caglar 11. caglar Lv 1 49 pts. 8,334
  2. Avatar for christioanchauvin 12. christioanchauvin Lv 1 46 pts. 8,328
  3. Avatar for martinzblavy 13. martinzblavy Lv 1 42 pts. 8,327
  4. Avatar for gitwut 14. gitwut Lv 1 39 pts. 8,317
  5. Avatar for nicobul 15. nicobul Lv 1 36 pts. 8,310
  6. Avatar for bamh 16. bamh Lv 1 33 pts. 8,300
  7. Avatar for reefyrob 17. reefyrob Lv 1 31 pts. 8,298
  8. Avatar for Mr_Jolty 18. Mr_Jolty Lv 1 28 pts. 8,294
  9. Avatar for goastano 19. goastano Lv 1 26 pts. 8,269
  10. Avatar for mirp 20. mirp Lv 1 24 pts. 8,264

Comments

beta_helix Staff Lv 1

This puzzle uses the new Disulfide Count Score Filter to address some of the problems pointed out by players when this puzzle was posted during CASP10:
http://fold.it/portal/node/992993#comment-18429
__________________

Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casp10/target.cgi?id=120
__________________

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

You can see that these secondary structure predictions imply that this protein is mostly loop!
__________________

Link to template PDBs:

http://www.pdb.org/pdb/explore/explore.do?structureId=1lu0
http://www.pdb.org/pdb/explore/explore.do?structureId=1w7z
http://www.pdb.org/pdb/explore/explore.do?structureId=1h9h

For those of you who miss your scripts, don't worry: the "normal" version of this puzzle will be reposted next week (allowing you to you to load in your manual saves from this puzzle).