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689: (Old) Hand-Folding CASP10 T0711 Repost

Closed since about 13 years ago

Intermediate

Summary

Created
March 20, 2013
Expires
Max points
100
Description

This puzzle has been reposted. Please use the new version of this puzzle, 689b. You may load your MANUAL saves into the new puzzle. We apologize for any inconvenience.

Top groups

  1. Avatar for Russian team 11. Russian team 2 pts. 8,261
  2. Avatar for Brony@Home 12. Brony@Home 1 pt. 8,260
  3. Avatar for Beta Folders 13. Beta Folders 1 pt. 8,198
  4. Avatar for 7Monkeys 14. 7Monkeys 1 pt. 8,186
  5. Avatar for Gargleblasters 15. Gargleblasters 1 pt. 8,178
  6. Avatar for Team Schleswig-Holstein 16. Team Schleswig-Holstein 1 pt. 8,139
  7. Avatar for DSN @ Home 17. DSN @ Home 1 pt. 7,979
  8. Avatar for HMT heritage 18. HMT heritage 1 pt. 4,699
  1. Avatar for Grom 21. Grom Lv 1 22 pts. 8,261
  2. Avatar for Pagdzin 22. Pagdzin Lv 1 20 pts. 8,260
  3. Avatar for drjr 23. drjr Lv 1 18 pts. 8,256
  4. Avatar for Jesse Pinkman 24. Jesse Pinkman Lv 1 17 pts. 8,253
  5. Avatar for tscherulli 25. tscherulli Lv 1 15 pts. 8,251
  6. Avatar for markm457 26. markm457 Lv 1 14 pts. 8,249
  7. Avatar for shankwiler 27. shankwiler Lv 1 12 pts. 8,248
  8. Avatar for larry25427 28. larry25427 Lv 1 11 pts. 8,247
  9. Avatar for pauldunn 29. pauldunn Lv 1 10 pts. 8,246
  10. Avatar for silverberg 30. silverberg Lv 1 9 pts. 8,243

Comments

beta_helix Staff Lv 1

This puzzle uses the new Disulfide Count Score Filter to address some of the problems pointed out by players when this puzzle was posted during CASP10:
http://fold.it/portal/node/992993#comment-18429
__________________

Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casp10/target.cgi?id=120
__________________

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

You can see that these secondary structure predictions imply that this protein is mostly loop!
__________________

Link to template PDBs:

http://www.pdb.org/pdb/explore/explore.do?structureId=1lu0
http://www.pdb.org/pdb/explore/explore.do?structureId=1w7z
http://www.pdb.org/pdb/explore/explore.do?structureId=1h9h

For those of you who miss your scripts, don't worry: the "normal" version of this puzzle will be reposted next week (allowing you to you to load in your manual saves from this puzzle).