beta_helix Staff Lv 1
This puzzle uses the new Disulfide Count Score Filter to address some of the problems pointed out by players when this puzzle was posted during CASP10:
http://fold.it/portal/node/992993#comment-18429
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Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casp10/target.cgi?id=120
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Here is the sequence logo predicted by the SAM server.
H = helix
E = sheet
C = loop (or coil)
The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.
You can see that these secondary structure predictions imply that this protein is mostly loop!
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Link to template PDBs:
http://www.pdb.org/pdb/explore/explore.do?structureId=1lu0
http://www.pdb.org/pdb/explore/explore.do?structureId=1w7z
http://www.pdb.org/pdb/explore/explore.do?structureId=1h9h
For those of you who miss your scripts, don't worry: the "normal" version of this puzzle will be reposted next week (allowing you to you to load in your manual saves from this puzzle).