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689: (Old) Hand-Folding CASP10 T0711 Repost

Closed since almost 13 years ago

Intermediate

Summary

Created
March 20, 2013
Expires
Max points
100
Description

This puzzle has been reposted. Please use the new version of this puzzle, 689b. You may load your MANUAL saves into the new puzzle. We apologize for any inconvenience.

Top groups

  1. Avatar for Void Crushers
    1. Void Crushers
    100 pts. 8,433
  2. Avatar for foldeRNA 2. foldeRNA 74 pts. 8,380
  3. Avatar for SETI.Germany 3. SETI.Germany 54 pts. 8,358
  4. Avatar for Deleted group 4. Deleted group pts. 8,352
  5. Avatar for L'Alliance Francophone 5. L'Alliance Francophone 27 pts. 8,342
  6. Avatar for Anthropic Dreams 6. Anthropic Dreams 18 pts. 8,342
  7. Avatar for FoldIt@Netherlands 7. FoldIt@Netherlands 12 pts. 8,336
  8. Avatar for Contenders 8. Contenders 8 pts. 8,327
  9. Avatar for Natural Abilities 9. Natural Abilities 5 pts. 8,294
  10. Avatar for Go Science 10. Go Science 3 pts. 8,264
  1. Avatar for jogie62 71. jogie62 Lv 1 1 pt. 7,607
  2. Avatar for Nymphette 72. Nymphette Lv 1 1 pt. 7,606
  3. Avatar for ingoneato 73. ingoneato Lv 1 1 pt. 7,553
  4. Avatar for frood66 74. frood66 Lv 1 1 pt. 6,617
  5. Avatar for histon 75. histon Lv 1 1 pt. 4,699
  6. Avatar for rinze 76. rinze Lv 1 1 pt. 4,699

Comments

beta_helix Staff Lv 1

This puzzle uses the new Disulfide Count Score Filter to address some of the problems pointed out by players when this puzzle was posted during CASP10:
http://fold.it/portal/node/992993#comment-18429
__________________

Here is the CASP link for this target (showing the amino acid sequence):
http://predictioncenter.org/casp10/target.cgi?id=120
__________________

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

You can see that these secondary structure predictions imply that this protein is mostly loop!
__________________

Link to template PDBs:

http://www.pdb.org/pdb/explore/explore.do?structureId=1lu0
http://www.pdb.org/pdb/explore/explore.do?structureId=1w7z
http://www.pdb.org/pdb/explore/explore.do?structureId=1h9h

For those of you who miss your scripts, don't worry: the "normal" version of this puzzle will be reposted next week (allowing you to you to load in your manual saves from this puzzle).