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693: Hand-Folding De-novo Freestyle 22

Closed since about 13 years ago

Intermediate Overall Prediction Hand-Folding

Summary


Created
March 27, 2013
Expires
Max points
100
Description

We are giving you another currently unsolved protein as an extended chain, but this time only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be re-posted and LUA scripts and sharing will be allowed. You'll be able to load in your solutions from this puzzle and use scripting and sharing. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

Top groups


  1. Avatar for Team Toombs 21. Team Toombs 1 pt. 8,431
  2. Avatar for DSN @ Home 22. DSN @ Home 1 pt. 7,870
  3. Avatar for Deleted group 23. Deleted group pts. 7,518
  4. Avatar for Eὕρηκα! Heureka! 24. Eὕρηκα! Heureka! 1 pt. 7,505
  5. Avatar for Rechenkraft.net 25. Rechenkraft.net 1 pt. 7,221
  6. Avatar for Window Group 26. Window Group 1 pt. 4,383

  1. Avatar for evnidetr 191. evnidetr Lv 1 2 pts. 8,584
  2. Avatar for yitzy 192. yitzy Lv 1 2 pts. 8,577
  3. Avatar for superleroy 193. superleroy Lv 1 2 pts. 8,574
  4. Avatar for pellswick 194. pellswick Lv 1 2 pts. 8,566
  5. Avatar for biklooost 195. biklooost Lv 1 2 pts. 8,560
  6. Avatar for lange 196. lange Lv 1 2 pts. 8,553
  7. Avatar for Goldschmidt 197. Goldschmidt Lv 1 2 pts. 8,534
  8. Avatar for Mr_Jolty 198. Mr_Jolty Lv 1 2 pts. 8,531
  9. Avatar for Farpanda 199. Farpanda Lv 1 2 pts. 8,526
  10. Avatar for Deleted player 200. Deleted player pts. 8,521

Comments


beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 32 & 42 are highly predicted to be part of a sheet. However, the Valines at residues 9 & 10 are highly predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.

beta_helix Staff Lv 1

Because this is the first Hand-Folding puzzle starting from an extended chain (without templates) we are giving you an extra week to use all your Hand-folding skills!