Placeholder image of a protein
Icon representing a puzzle

693: Hand-Folding De-novo Freestyle 22

Closed since almost 13 years ago

Intermediate Overall Prediction Hand-Folding

Summary


Created
March 27, 2013
Expires
Max points
100
Description

We are giving you another currently unsolved protein as an extended chain, but this time only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be re-posted and LUA scripts and sharing will be allowed. You'll be able to load in your solutions from this puzzle and use scripting and sharing. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

Top groups


  1. Avatar for Deleted group pts. 9,666
  2. Avatar for Void Crushers 2. Void Crushers 82 pts. 9,616
  3. Avatar for Contenders 3. Contenders 66 pts. 9,603
  4. Avatar for Anthropic Dreams 4. Anthropic Dreams 53 pts. 9,603
  5. Avatar for Team Schleswig-Holstein 5. Team Schleswig-Holstein 42 pts. 9,481
  6. Avatar for Go Science 6. Go Science 33 pts. 9,440
  7. Avatar for L'Alliance Francophone 7. L'Alliance Francophone 26 pts. 9,424
  8. Avatar for HMT heritage 8. HMT heritage 20 pts. 9,406
  9. Avatar for Beta Folders 9. Beta Folders 15 pts. 9,312
  10. Avatar for Russian team 10. Russian team 11 pts. 9,133

  1. Avatar for gramps 91. gramps Lv 1 21 pts. 9,075
  2. Avatar for Deleted player 92. Deleted player pts. 9,072
  3. Avatar for SouperGenious 93. SouperGenious Lv 1 20 pts. 9,069
  4. Avatar for Jesse Pinkman 94. Jesse Pinkman Lv 1 20 pts. 9,067
  5. Avatar for ViJay7019 95. ViJay7019 Lv 1 19 pts. 9,061
  6. Avatar for qasw 96. qasw Lv 1 19 pts. 9,049
  7. Avatar for KingLear 97. KingLear Lv 1 19 pts. 9,049
  8. Avatar for guineapig 98. guineapig Lv 1 18 pts. 9,042
  9. Avatar for versat82 99. versat82 Lv 1 18 pts. 9,042
  10. Avatar for ComputerMage 100. ComputerMage Lv 1 17 pts. 9,037

Comments


beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 32 & 42 are highly predicted to be part of a sheet. However, the Valines at residues 9 & 10 are highly predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.

beta_helix Staff Lv 1

Because this is the first Hand-Folding puzzle starting from an extended chain (without templates) we are giving you an extra week to use all your Hand-folding skills!