Placeholder image of a protein
Icon representing a puzzle

698 (<15): Human cancer protein interaction network target

Closed since almost 13 years ago

Beginner Overall Prediction

Summary

Created
April 06, 2013
Expires
Max points
100
Description

The solution structure of this dead ringer-like protein has already been solved using NMR, but the crystal structure has yet to be released. We are giving you all 20 models from the NMR ensemble. Every time you reset the puzzle it will cycle through these 20 structures and they are available in the Alignment Tool so you can use partial threading between them. We look forward to seeing how close to the crystal structure you are able to get! For players with fewer than 15 global points.

Top groups

  1. Avatar for Richard Dawkins Foundation
    1. Richard Dawkins Foundation
    100 pts. 11,221
  2. Avatar for L'Alliance Francophone 2. L'Alliance Francophone 52 pts. 11,068
  3. Avatar for Eὕρηκα! Heureka! 3. Eὕρηκα! Heureka! 24 pts. 10,889
  4. Avatar for Go Science 4. Go Science 10 pts. 10,855
  5. Avatar for Void Crushers 5. Void Crushers 4 pts. 10,827
  6. Avatar for The Minecrafters 6. The Minecrafters 1 pt. 10,782
  7. Avatar for Deleted group 7. Deleted group pts. 10,353
  8. Avatar for Protein structural analysis room Japan 8. Protein structural analysis room Japan 1 pt. 9,741
  9. Avatar for ricg test group 9. ricg test group 1 pt. 8,235
  1. Avatar for billsabob 261. billsabob Lv 1 1 pt. 8,894
  2. Avatar for AD_89 262. AD_89 Lv 1 1 pt. 8,871
  3. Avatar for Hamstarr 263. Hamstarr Lv 1 1 pt. 8,855
  4. Avatar for Chema96 264. Chema96 Lv 1 1 pt. 8,749
  5. Avatar for Blackmesa34 265. Blackmesa34 Lv 1 1 pt. 8,745
  6. Avatar for Ginnyg 266. Ginnyg Lv 1 1 pt. 8,570
  7. Avatar for sciencegeek245 267. sciencegeek245 Lv 1 1 pt. 8,425
  8. Avatar for ktspecner 268. ktspecner Lv 1 1 pt. 8,409
  9. Avatar for cfxh 269. cfxh Lv 1 1 pt. 8,276
  10. Avatar for Kalos Angel 270. Kalos Angel Lv 1 1 pt. 8,242

Comments

beta_helix Staff Lv 1

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

Additional information on partial threading here:
http://fold.it/portal/node/989193#comment-9965
_____________

If you want to fold proteins, know that there are many way to play and this variety is the main value of Foldit :

  • try all puzzles not only "beginners" one,
  • fold first the ones you like the most,
  • try by yourself to understand what works and what doesn't,
  • make your own strategy and at least try more than one, here some other strategies to play QTTN http://foldit.wikia.com/wiki/101_-_Puzzle_Levels_and_Types,
  • ask for tips in global when you think you doesn't understand something.

Make sure you have followed these tutorials:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing
    before starting this puzzle.