Placeholder image of a protein
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698 (<150): Human cancer protein interaction network target

Closed since almost 13 years ago

Beginner Overall Prediction

Summary

Created
April 06, 2013
Expires
Max points
100
Description

The solution structure of this dead ringer-like protein has already been solved using NMR, but the crystal structure has yet to be released. We are giving you all 20 models from the NMR ensemble. Every time you reset the puzzle it will cycle through these 20 structures and they are available in the Alignment Tool so you can use partial threading between them. We look forward to seeing how close to the crystal structure you are able to get! For players with fewer than 150 global points.

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Comments

beta_helix Staff Lv 1

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

Additional information on partial threading here:
http://fold.it/portal/node/989193#comment-9965
_____________

If you want to fold proteins, know that there are many way to play and this variety is the main value of Foldit :

  • try all puzzles not only "beginners" one,
  • fold first the ones you like the most,
  • try by yourself to understand what works and what doesn't,
  • make your own strategy and at least try more than one, here some other strategies to play QTTN http://foldit.wikia.com/wiki/101_-_Puzzle_Levels_and_Types,
  • ask for tips in global when you think you doesn't understand something.

Make sure you have followed these tutorials:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing
    before starting this puzzle.