Placeholder image of a protein
Icon representing a puzzle

Beginner Puzzle (<15): Killer Toxin

Closed since over 12 years ago

Beginner Beginner

Summary

Created
May 20, 2013
Expires
Max points
100
Description

Ustilago maydis is a fungal pathogen of maize, some strains of which secrete killer toxins. This is a short 79-residue protein for new players to try out after completing the Introductory Puzzles. The native is shown as a guide on this puzzle, so try using everything you have learned in the Intro levels to match the native fold. For players with fewer than 15 global points.

Top groups

  1. Avatar for Anthropic Dreams
    1. Anthropic Dreams
    100 pts. 9,614
  2. Avatar for Richard Dawkins Foundation 2. Richard Dawkins Foundation 60 pts. 9,550
  3. Avatar for ricg test group 3. ricg test group 33 pts. 9,527
  4. Avatar for Deleted group 4. Deleted group pts. 9,153
  5. Avatar for foldeRNA 5. foldeRNA 8 pts. 9,126
  6. Avatar for Trinity 6. Trinity 4 pts. 9,049
  7. Avatar for Go Science 7. Go Science 2 pts. 9,018
  8. Avatar for Nerdfighters 8. Nerdfighters 1 pt. 8,916
  9. Avatar for Russian team 9. Russian team 1 pt. 8,843
  10. Avatar for Team China 10. Team China 1 pt. 8,771
  1. Avatar for proteinabq 241. proteinabq Lv 1 2 pts. 8,904
  2. Avatar for ihaller 242. ihaller Lv 1 2 pts. 8,904
  3. Avatar for dwabado 243. dwabado Lv 1 2 pts. 8,902
  4. Avatar for Campayne 244. Campayne Lv 1 2 pts. 8,902
  5. Avatar for shanold 245. shanold Lv 1 2 pts. 8,902
  6. Avatar for BrotherPhoenix 246. BrotherPhoenix Lv 1 2 pts. 8,901
  7. Avatar for BumbleRumble 247. BumbleRumble Lv 1 2 pts. 8,901
  8. Avatar for Feldar 248. Feldar Lv 1 2 pts. 8,901
  9. Avatar for slippedhal0 249. slippedhal0 Lv 1 2 pts. 8,900
  10. Avatar for BioEnchanted 250. BioEnchanted Lv 1 2 pts. 8,900

Comments

tjbertram Lv 1

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

If you want to fold proteins, know that there are many way to play and this variety is the main value of Foldit :

  • try all puzzles not only "beginners" one,
  • fold first the ones you like the most,
  • try by yourself to understand what works and what doesn't,
  • make your own strategy and at least try more than one, here some other strategies to play QTTN http://foldit.wikia.com/wiki/101_-_Puzzle_Levels_and_Types,
  • ask for tips in global when you think you doesn't understand something.

Make sure you have followed these tutorials:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • quest to the native
  • control over clashing
    before starting this puzzle.