Placeholder image of a protein
Icon representing a puzzle

Beginner Puzzle (<150): Killer Toxin

Closed since over 12 years ago

Beginner Beginner

Summary

Created
May 20, 2013
Expires
Max points
100
Description

Ustilago maydis is a fungal pathogen of maize, some strains of which secrete killer toxins. This is a short 79-residue protein for new players to try out after completing the Introductory Puzzles. The native is shown as a guide on this puzzle, so try using everything you have learned in the Intro levels to match the native fold. For players with fewer than 150 global points.

Top groups

  1. Avatar for Anthropic Dreams
    1. Anthropic Dreams
    100 pts. 9,567
  2. Avatar for Richard Dawkins Foundation 2. Richard Dawkins Foundation 65 pts. 9,538
  3. Avatar for SETIKAH@KOREA 3. SETIKAH@KOREA 41 pts. 9,496
  4. Avatar for Freedom Folders 4. Freedom Folders 24 pts. 9,296
  5. Avatar for Crunching Family 5. Crunching Family 14 pts. 9,242
  6. Avatar for :) 6. :) 7 pts. 9,229
  7. Avatar for Void Crushers 7. Void Crushers 4 pts. 9,200
  8. Avatar for Team Germany 8. Team Germany 2 pts. 9,120
  9. Avatar for ricg test group 9. ricg test group 1 pt. 9,078
  10. Avatar for Go Science 10. Go Science 1 pt. 8,929
  1. Avatar for CoachB 71. CoachB Lv 1 15 pts. 9,149
  2. Avatar for TedStudley 72. TedStudley Lv 1 14 pts. 9,147
  3. Avatar for CaroBearo 73. CaroBearo Lv 1 14 pts. 9,145
  4. Avatar for relaxmax 74. relaxmax Lv 1 13 pts. 9,144
  5. Avatar for Kiytan 75. Kiytan Lv 1 13 pts. 9,143
  6. Avatar for EMPSHOK 76. EMPSHOK Lv 1 12 pts. 9,131
  7. Avatar for kvacek 77. kvacek Lv 1 12 pts. 9,121
  8. Avatar for biochemist93 78. biochemist93 Lv 1 12 pts. 9,120
  9. Avatar for alexliver 79. alexliver Lv 1 11 pts. 9,107
  10. Avatar for ShanesMolting 80. ShanesMolting Lv 1 11 pts. 9,097

Comments

tjbertram Lv 1

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

If you want to fold proteins, know that there are many way to play and this variety is the main value of Foldit :

  • try all puzzles not only "beginners" one,
  • fold first the ones you like the most,
  • try by yourself to understand what works and what doesn't,
  • make your own strategy and at least try more than one, here some other strategies to play QTTN http://foldit.wikia.com/wiki/101_-_Puzzle_Levels_and_Types,
  • ask for tips in global when you think you doesn't understand something.

Make sure you have followed these tutorials:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • quest to the native
  • control over clashing
    before starting this puzzle.