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728: De-novo Freestyle 25: Hand-folding Round

Closed since almost 13 years ago

Intermediate Overall Prediction Hand-Folding

Summary


Created
June 10, 2013
Expires
Max points
100
Description

We are giving you another currently unsolved protein as an extended chain. This round only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be re-posted and LUA scripts and sharing will be allowed. You'll be able to load in your solutions from this puzzle and use scripting and sharing. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

Top groups


  1. Avatar for Window Group 21. Window Group 1 pt. 7,292
  2. Avatar for incognito group 22. incognito group 1 pt. 7,068
  3. Avatar for Cannabis Crew 23. Cannabis Crew 1 pt. 5,076
  4. Avatar for DSN @ Home 24. DSN @ Home 1 pt. 3,941
  5. Avatar for ricg test group 25. ricg test group 1 pt. 3,935
  6. Avatar for Super Happy Fun Time 26. Super Happy Fun Time 1 pt. 3,935

  1. Avatar for eikem 21. eikem Lv 1 69 pts. 10,726
  2. Avatar for CheezWhiz 22. CheezWhiz Lv 1 67 pts. 10,722
  3. Avatar for vakobo 23. vakobo Lv 1 66 pts. 10,716
  4. Avatar for gdnskye 24. gdnskye Lv 1 65 pts. 10,710
  5. Avatar for martinzblavy 25. martinzblavy Lv 1 63 pts. 10,701
  6. Avatar for hansvandenhof 26. hansvandenhof Lv 1 62 pts. 10,701
  7. Avatar for Mr_Jolty 27. Mr_Jolty Lv 1 61 pts. 10,699
  8. Avatar for O Seki To 28. O Seki To Lv 1 60 pts. 10,698
  9. Avatar for pgiles 29. pgiles Lv 1 58 pts. 10,688
  10. Avatar for cbwest 30. cbwest Lv 1 57 pts. 10,686

Comments


beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Alanines at residues 117-119, 121-122 and 130 are highly predicted to be part of a helix. However, the Alanines at residues 3 and 80 are not predicted to be anything!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.