Placeholder image of a protein
Icon representing a puzzle

738: De-novo Freestyle 26: Hand-folding Round

Closed since over 12 years ago

Intermediate Overall Prediction Hand-Folding

Summary


Created
July 02, 2013
Expires
Max points
100
Description

This is a funny little protein that was designed by scientists in the Baker lab. It has only been crystallized as a dimer, but it is known to exist in solution as a monomer. This round only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be re-posted and LUA scripts and sharing will be allowed. You'll be able to load in your solutions from this puzzle and use scripting and sharing. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

Top groups


  1. Avatar for SETI.Germany 11. SETI.Germany 8 pts. 10,499
  2. Avatar for FoldIt@Netherlands 12. FoldIt@Netherlands 6 pts. 10,322
  3. Avatar for Russian team 13. Russian team 4 pts. 10,235
  4. Avatar for :) 15. :) 2 pts. 9,909
  5. Avatar for Deleted group 16. Deleted group pts. 9,767
  6. Avatar for It's over 9000! 17. It's over 9000! 1 pt. 9,633
  7. Avatar for Natural Abilities 18. Natural Abilities 1 pt. 9,547
  8. Avatar for Deleted group 19. Deleted group pts. 9,101
  9. Avatar for SETIKAH@KOREA 20. SETIKAH@KOREA 1 pt. 8,575

  1. Avatar for Steven Pletsch
    1. Steven Pletsch Lv 1
    100 pts. 11,360
  2. Avatar for drumpeter18yrs9yrs 2. drumpeter18yrs9yrs Lv 1 98 pts. 11,325
  3. Avatar for Mark- 3. Mark- Lv 1 96 pts. 11,292
  4. Avatar for karstenw 4. karstenw Lv 1 94 pts. 11,243
  5. Avatar for martinzblavy 5. martinzblavy Lv 1 92 pts. 11,220
  6. Avatar for bertro 6. bertro Lv 1 90 pts. 11,181
  7. Avatar for spmm 7. spmm Lv 1 88 pts. 11,158
  8. Avatar for pauldunn 8. pauldunn Lv 1 86 pts. 11,153
  9. Avatar for Madde 9. Madde Lv 1 84 pts. 11,127
  10. Avatar for MurloW 10. MurloW Lv 1 82 pts. 11,071

Comments


bkoep Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 6 & 7 are highly predicted to be part of a sheet. However, the Valines at residues 64 & 65 are highly predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.