Placeholder image of a protein
Icon representing a puzzle

757: De-novo Freestyle 27: Hand-folding Round

Closed since over 12 years ago

Intermediate Overall Prediction Hand-Folding

Summary


Created
August 05, 2013
Expires
Max points
100
Description

We are giving you another currently unsolved protein as an extended chain. This round only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be re-posted and LUA scripts and sharing will be allowed. You'll be able to load in your solutions from this puzzle and use scripting and sharing. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

Top groups


  1. Avatar for Deleted group pts. 10,864
  2. Avatar for Contenders 2. Contenders 79 pts. 10,835
  3. Avatar for Anthropic Dreams 3. Anthropic Dreams 61 pts. 10,801
  4. Avatar for Void Crushers 4. Void Crushers 47 pts. 10,724
  5. Avatar for Deleted group 5. Deleted group pts. 10,691
  6. Avatar for L'Alliance Francophone 6. L'Alliance Francophone 26 pts. 10,555
  7. Avatar for Go Science 7. Go Science 19 pts. 10,535
  8. Avatar for Gargleblasters 8. Gargleblasters 14 pts. 10,412
  9. Avatar for Beta Folders 9. Beta Folders 10 pts. 10,366
  10. Avatar for Brony@Home 10. Brony@Home 7 pts. 10,153

  1. Avatar for SKSbell 61. SKSbell Lv 1 17 pts. 9,991
  2. Avatar for gdnskye 62. gdnskye Lv 1 17 pts. 9,976
  3. Avatar for joremen 63. joremen Lv 1 16 pts. 9,975
  4. Avatar for steveB 64. steveB Lv 1 16 pts. 9,956
  5. Avatar for grogar7 65. grogar7 Lv 1 15 pts. 9,939
  6. Avatar for LociOiling 66. LociOiling Lv 1 15 pts. 9,928
  7. Avatar for heather-1 67. heather-1 Lv 1 14 pts. 9,928
  8. Avatar for pvc78 68. pvc78 Lv 1 14 pts. 9,923
  9. Avatar for rsladew 69. rsladew Lv 1 13 pts. 9,911
  10. Avatar for ViJay7019 70. ViJay7019 Lv 1 13 pts. 9,896

Comments


bkoep Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Glutamate at residue 15 is highly predicted to be part of a sheet. However, the Glutamates at residues 80 & 81 are weakly predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.