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767: De-novo Freestyle 28: Hand-folding Round

Closed since over 12 years ago

Intermediate Overall Prediction Hand-Folding

Summary


Created
August 22, 2013
Expires
Max points
100
Description

We are giving you another currently unsolved protein as an extended chain. This round only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be re-posted and LUA scripts and sharing will be allowed. You'll be able to load in your solutions from this puzzle and use scripting and sharing. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

Top groups


  1. Avatar for DSN @ Home 21. DSN @ Home 1 pt. 4,484
  2. Avatar for Brony@Home 22. Brony@Home 1 pt. 0
  3. Avatar for foldeRNA 23. foldeRNA 1 pt. 0
  4. Avatar for ricg test group 24. ricg test group 1 pt. 0

  1. Avatar for gloverd 161. gloverd Lv 1 1 pt. 8,692
  2. Avatar for pa.vi 162. pa.vi Lv 1 1 pt. 8,683
  3. Avatar for Erinys 163. Erinys Lv 1 1 pt. 8,642
  4. Avatar for martinf 164. martinf Lv 1 1 pt. 8,636
  5. Avatar for perrystaff 165. perrystaff Lv 1 1 pt. 8,628
  6. Avatar for bob1928 166. bob1928 Lv 1 1 pt. 8,626
  7. Avatar for cmendo 167. cmendo Lv 1 1 pt. 8,555
  8. Avatar for persephone977 168. persephone977 Lv 1 1 pt. 8,543
  9. Avatar for armadillo314 169. armadillo314 Lv 1 1 pt. 8,534
  10. Avatar for HoodRoof 170. HoodRoof Lv 1 1 pt. 8,527

Comments


bkoep Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 84-87 is highly predicted to be part of a sheet. However, the Valines at residues 117 & 121 are predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.