779: Unsolved Salmonella Bacteriophage: Trimmed Cryo-electron Density

Closed since over 12 years ago

Summary

• Created: September 17, 2013
• Expires: September 25, 2013 at 18:00 UTC
• Max points: 100

Description

This is a repost of Puzzle 772, but this time we have more aggressively trimmed the density map. You can load in your solutions from the previous puzzles (737, 740, 749, 756, 765, and 772) and can find more details in the puzzle comments.

Top groups

• 11. Beta Folders 4 pts. 11,185
• 12. Russian team 2 pts. 10,982
• 13. FoldIt@Netherlands 2 pts. 10,897
• 14. Natural Abilities 1 pt. 10,722
• 15. Deleted group pts. 10,666
• 16. Curtin Crowd 1 pt. 10,365
• 17. Cell Biology Smith Fall 2013 1 pt. 9,965
• 18. Deleted group pts. 7,192
• 19. Richard Dawkins Foundation 1 pt. 6,603
• 20. test_group1 1 pt. 3,401

Top soloists

• 11. bob1928 69 pts. 11,483
• 12. Incongruous 66 pts. 11,459
• 13. cbwest 64 pts. 11,417
• 14. Bautho 61 pts. 11,405
• 15. hpaege 59 pts. 11,325
• 16. Galaxie 56 pts. 11,307
• 17. MurloW 54 pts. 11,303
• 18. diamond_dust 52 pts. 11,287
• 19. cobaltteal 50 pts. 11,268
• 20. Jim Fraser 48 pts. 11,265

Comments

[bkoep]

NOTE: If you did not manually save a solution that you want to use from puzzles 737, 740, 749, 756, 765, or 772, you can go back to those puzzles, manually save it, and the solution should appear in your manual saves for this puzzle.

Original secondary structure predictions from the SAM server are here:
http://fold.it/portal/node/995398#comment-23593

More info about Cryo-electron microscopy here:

en.wikipedia.org

Cryogenic electron microscopy

Cryogenic electron microscopy (cryo-EM) is a cryomicroscopy technique applied on samples cooled to cryogenic temperatures. For biological specimens, the structure is preserved by embedding in an environment of vitreous ice. An aqueous sample solution is applied to a grid-mesh and plunge-frozen in liquid ethane or a mixture of liquid ethane and propane. While development of the technique began in the 1970s, recent advances in detector technology and software algorithms have allowed for the dete In...

[beta_helix]

You might be wondering why this puzzle does not have any starting models from the previous round.
We are almost finished analyzing your solutions from 772 and as soon as we are done we'll repost this puzzle as 779b with those starting structures as well (and of course allowing you to load in all your manual saves).

Since our analysis might not be finished until tomorrow, however, we wanted to let you work with this new trimmed density map until then.
We know that this particular protein has been tough, but we hope that the new trimmed map on this puzzle is helpful to you!