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784: De-Novo Freestyle 31 with Predicted Contacts

Closed since over 12 years ago

Intermediate Overall Prediction

Summary


Created
September 22, 2013
Expires
Max points
100
Description

This is the first puzzle to include a new kind of data: Predicted Contacts. You can see the predicted contacts for this protein by clicking the Contact Map button in the Main menu (Selection Interface) or in the Actions tab (Classic Interface). Blue squares represent predicted contacts; a darker blue color means there is stronger evidence for a contact prediction. There is a score multiplier that increases whenever you bring together two residues that make a predicted contact. Find a high-scoring fold that satisfies the most contact predictions!

Top groups


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  6. Avatar for DodoBird 156. DodoBird Lv 1 2 pts. 16,236
  7. Avatar for Tac1 157. Tac1 Lv 1 1 pt. 15,985
  8. Avatar for armadillo314 158. armadillo314 Lv 1 1 pt. 15,877
  9. Avatar for darioarena 159. darioarena Lv 1 1 pt. 15,538
  10. Avatar for harp 160. harp Lv 1 1 pt. 15,153

Comments


bkoep Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 2 & 3 are highly predicted to be part of a sheet. However, the Valines at residue 34 is predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.