Placeholder image of a protein
Icon representing a puzzle

784: De-Novo Freestyle 31 with Predicted Contacts

Closed since over 12 years ago

Intermediate Overall Prediction

Summary


Created
September 22, 2013
Expires
Max points
100
Description

This is the first puzzle to include a new kind of data: Predicted Contacts. You can see the predicted contacts for this protein by clicking the Contact Map button in the Main menu (Selection Interface) or in the Actions tab (Classic Interface). Blue squares represent predicted contacts; a darker blue color means there is stronger evidence for a contact prediction. There is a score multiplier that increases whenever you bring together two residues that make a predicted contact. Find a high-scoring fold that satisfies the most contact predictions!

Top groups


  1. Avatar for Void Crushers 100 pts. 28,901
  2. Avatar for Go Science 2. Go Science 84 pts. 28,702
  3. Avatar for Anthropic Dreams 3. Anthropic Dreams 70 pts. 28,417
  4. Avatar for Contenders 4. Contenders 58 pts. 28,220
  5. Avatar for Deleted group 5. Deleted group pts. 28,161
  6. Avatar for Gargleblasters 6. Gargleblasters 39 pts. 26,752
  7. Avatar for L'Alliance Francophone 7. L'Alliance Francophone 32 pts. 26,484
  8. Avatar for SETI.Germany 8. SETI.Germany 26 pts. 25,910
  9. Avatar for Beta Folders 9. Beta Folders 20 pts. 25,680
  10. Avatar for HMT heritage 10. HMT heritage 16 pts. 25,632

  1. Avatar for tokens 241. tokens Lv 1 1 pt. 0
  2. Avatar for NicoleHewitt 242. NicoleHewitt Lv 1 1 pt. 0
  3. Avatar for AsDawnBreaks 243. AsDawnBreaks Lv 1 1 pt. 0
  4. Avatar for naitram 244. naitram Lv 1 1 pt. 0
  5. Avatar for mwg10 245. mwg10 Lv 1 1 pt. 0
  6. Avatar for bronovitskiy 246. bronovitskiy Lv 1 1 pt. 0
  7. Avatar for Biosphere 247. Biosphere Lv 1 1 pt. 0
  8. Avatar for steveB 248. steveB Lv 1 1 pt. 0
  9. Avatar for Rita_Gat 249. Rita_Gat Lv 1 1 pt. 0
  10. Avatar for DaintyClaws 250. DaintyClaws Lv 1 1 pt. 0

Comments


bkoep Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 2 & 3 are highly predicted to be part of a sheet. However, the Valines at residue 34 is predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.