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807: De-novo Cryo-electron Density: Hand-folding Round

Closed since over 12 years ago

Advanced Overall Prediction Electron Density Hand-Folding

Summary

Created
November 07, 2013
Expires
Max points
100
Description

Try to fit this extended chain into the cryo-EM density cloud to gain points. This round only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be re-posted and LUA scripts and sharing will be allowed. You'll be able to load in your solutions from this puzzle and use scripting and sharing.

Top groups

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  3. Avatar for Brony@Home 23. Brony@Home 1 pt. 0
  4. Avatar for DSN @ Home 24. DSN @ Home 1 pt. 0
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  1. Avatar for ruchira.roy 191. ruchira.roy Lv 1 1 pt. 2,092
  2. Avatar for montadar 192. montadar Lv 1 1 pt. 2,076
  3. Avatar for Poshie 193. Poshie Lv 1 1 pt. 2,053
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  5. Avatar for kddickson42 195. kddickson42 Lv 1 1 pt. 1,997
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  7. Avatar for katanyag 197. katanyag Lv 1 1 pt. 1,953
  8. Avatar for Paul Bru 198. Paul Bru Lv 1 1 pt. 1,936
  9. Avatar for cccccc651 199. cccccc651 Lv 1 1 pt. 1,923
  10. Avatar for jtromposch 200. jtromposch Lv 1 1 pt. 1,916

Comments

beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valines at residues 41-42 are highly predicted to be part of a helix. However, the Valines at residue 67 and 94 are predicted to be in sheets!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).
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