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815: Revisiting Puzzle 87: Zinc Binding Protein

Closed since over 12 years ago

Intermediate Overall Prediction

Summary

Created
November 27, 2013
Expires
Max points
100
Description

This is a throwback puzzle to the early days of Foldit. A type of metal binding protein. We are revisiting old Foldit puzzles so we can see how useful the recent additions to the game have been. Players will NOT be able to load in any previous solutions for these puzzles.

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Comments

tjbertram Lv 1

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864
_____________
If you want to fold proteins, know that there are many ways to play and this variety is the main value of Foldit:

  • try all puzzles not only "beginner" ones,
  • fold first the ones you like the most,
  • try by yourself to understand what works and what doesn't,
  • ask for tips in global when you think you doesn't understand something.

Make sure you have followed these tutorials:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing

before starting this puzzle.
_____________
Original Puzzle:
http://fold.it/portal/node/451446

brow42 Lv 1

This is a pretty fascinating puzzle. It wasn't long before I had a fairly natural looking fold that ALSO had a tight symmetric cluster of 4 cysteines and 2 histidines. I'm not sure how to distribute my bridges, or how many bridges I should have. As my score increased, things started to wander apart. Any suggestions for how the active site should look?