Placeholder image of a protein
Icon representing a puzzle

823: Large CASP ROLL Target R0044

Closed since over 12 years ago

Intermediate Intermediate Overall Overall Prediction Prediction CASP ROLL CASP ROLL

Summary


Created
December 15, 2013
Expires
Max points
100
Description

This unsolved CASP ROLL target is larger than most Foldit puzzles, at 204 residues. There are no homologs, so we are starting you from an extended chain. After this puzzle closes, there will be one more round with server predictions. See the puzzle comments for secondary structure predictions.

Top groups


  1. Avatar for HMT heritage 11. HMT heritage 7 pts. 11,531
  2. Avatar for SETI.Germany 12. SETI.Germany 5 pts. 11,490
  3. Avatar for Repro-men 13. Repro-men 4 pts. 11,463
  4. Avatar for FoldIt@Netherlands 15. FoldIt@Netherlands 2 pts. 11,030
  5. Avatar for Natural Abilities 16. Natural Abilities 1 pt. 10,801
  6. Avatar for FoldIt@Poland 17. FoldIt@Poland 1 pt. 10,033
  7. Avatar for Palmer High Biology 19. Palmer High Biology 1 pt. 9,171

  1. Avatar for ViJay7019 71. ViJay7019 Lv 1 20 pts. 11,030
  2. Avatar for goastano 72. goastano Lv 1 20 pts. 10,997
  3. Avatar for pgiles 73. pgiles Lv 1 19 pts. 10,972
  4. Avatar for KingLear 74. KingLear Lv 1 19 pts. 10,927
  5. Avatar for SKSbell 75. SKSbell Lv 1 18 pts. 10,912
  6. Avatar for dpmattingly 76. dpmattingly Lv 1 18 pts. 10,861
  7. Avatar for alcor29 77. alcor29 Lv 1 17 pts. 10,848
  8. Avatar for Mr_Jolty 78. Mr_Jolty Lv 1 17 pts. 10,801
  9. Avatar for dnpw1 79. dnpw1 Lv 1 16 pts. 10,797
  10. Avatar for Merf 80. Merf Lv 1 16 pts. 10,792

Comments


bkoep Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Glutamates at residues 27 & 28 are predicted to be in a helix. However, the Glutamates at residues 159 & 161 are predicted to be part of a sheet!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.

bkoep Staff Lv 1

When Puzzle 823 closes, we'll post a follow-up puzzle for this CASP ROLL target with server predictions. We can extend the deadline for the follow-up puzzle if you would like.