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823: Large CASP ROLL Target R0044

Closed since over 12 years ago

Intermediate Intermediate Overall Overall Prediction Prediction CASP ROLL CASP ROLL

Summary


Created
December 15, 2013
Expires
Max points
100
Description

This unsolved CASP ROLL target is larger than most Foldit puzzles, at 204 residues. There are no homologs, so we are starting you from an extended chain. After this puzzle closes, there will be one more round with server predictions. See the puzzle comments for secondary structure predictions.

Top groups


  1. Avatar for Deleted group 21. Deleted group pts. 7,819
  2. Avatar for Crunching Family 22. Crunching Family 1 pt. 7,577
  3. Avatar for DSN @ Home 23. DSN @ Home 1 pt. 0
  4. Avatar for Deleted group 24. Deleted group pts. 0
  5. Avatar for Brony@Home 25. Brony@Home 1 pt. 0

  1. Avatar for aspadistra 251. aspadistra Lv 1 1 pt. 0
  2. Avatar for Euphuism 252. Euphuism Lv 1 1 pt. 0
  3. Avatar for psymunkees 253. psymunkees Lv 1 1 pt. 0
  4. Avatar for Caridorc 254. Caridorc Lv 1 1 pt. 0
  5. Avatar for greepski 255. greepski Lv 1 1 pt. 0

Comments


bkoep Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Glutamates at residues 27 & 28 are predicted to be in a helix. However, the Glutamates at residues 159 & 161 are predicted to be part of a sheet!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.

bkoep Staff Lv 1

When Puzzle 823 closes, we'll post a follow-up puzzle for this CASP ROLL target with server predictions. We can extend the deadline for the follow-up puzzle if you would like.