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830: De-novo Freestyle 32: Hand-folding Round

Closed since about 12 years ago

Intermediate Overall Prediction Hand-Folding

Summary


Created
January 03, 2014
Expires
Max points
100
Description

We are giving you another currently unsolved protein as an extended chain. This round only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be re-posted and LUA scripts and sharing will be allowed. You'll be able to load in your solutions from this puzzle and use scripting and sharing. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

Top groups


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  7. Avatar for uneRx 19. uneRx 1 pt. 8,580
  8. Avatar for Crunching Family 20. Crunching Family 1 pt. 8,452

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  3. Avatar for galactobourico 143. galactobourico Lv 1 2 pts. 9,427
  4. Avatar for mirjamvandelft 144. mirjamvandelft Lv 1 2 pts. 9,426
  5. Avatar for JPC119 145. JPC119 Lv 1 2 pts. 9,404
  6. Avatar for micheldeweerd 146. micheldeweerd Lv 1 2 pts. 9,400
  7. Avatar for CoachB 147. CoachB Lv 1 2 pts. 9,386
  8. Avatar for pruneau_44 148. pruneau_44 Lv 1 2 pts. 9,372
  9. Avatar for tela 149. tela Lv 1 2 pts. 9,343
  10. Avatar for Cerzax 150. Cerzax Lv 1 2 pts. 9,330

Comments


bkoep Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Leucines at residues 42 & 43 are highly predicted to be part of a sheet. However, the Leucine at residue 7 is predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.