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830: De-novo Freestyle 32: Hand-folding Round

Closed since about 12 years ago

Intermediate Overall Prediction Hand-Folding

Summary


Created
January 03, 2014
Expires
Max points
100
Description

We are giving you another currently unsolved protein as an extended chain. This round only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be re-posted and LUA scripts and sharing will be allowed. You'll be able to load in your solutions from this puzzle and use scripting and sharing. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

Top groups


  1. Avatar for Fold for Science 1 22. Fold for Science 1 1 pt. 8,020
  2. Avatar for It's over 9000! 23. It's over 9000! 1 pt. 7,945
  3. Avatar for Storm 24. Storm 1 pt. 7,936
  4. Avatar for BOINC@Odessa 25. BOINC@Odessa 1 pt. 7,777
  5. Avatar for DSN @ Home 26. DSN @ Home 1 pt. 7,059
  6. Avatar for Deleted group 27. Deleted group pts. 0

  1. Avatar for Tac1 181. Tac1 Lv 1 1 pt. 8,741
  2. Avatar for Cyanobacteria 182. Cyanobacteria Lv 1 1 pt. 8,735
  3. Avatar for persephone977 183. persephone977 Lv 1 1 pt. 8,613
  4. Avatar for athibeault1 184. athibeault1 Lv 1 1 pt. 8,580
  5. Avatar for Viz 185. Viz Lv 1 1 pt. 8,552
  6. Avatar for Reductone 186. Reductone Lv 1 1 pt. 8,517
  7. Avatar for Huckel4plus2 187. Huckel4plus2 Lv 1 1 pt. 8,481
  8. Avatar for jermainiac 188. jermainiac Lv 1 1 pt. 8,478
  9. Avatar for LordJvS 189. LordJvS Lv 1 1 pt. 8,472
  10. Avatar for leprechaun 190. leprechaun Lv 1 1 pt. 8,452

Comments


bkoep Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Leucines at residues 42 & 43 are highly predicted to be part of a sheet. However, the Leucine at residue 7 is predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.