Placeholder image of a protein
Icon representing a puzzle

838: De-novo Freestyle 33: Hand-folding Round

Closed since about 12 years ago

Intermediate Overall Prediction Hand-Folding

Summary


Created
January 27, 2014
Expires
Max points
100
Description

We are giving you another currently unsolved protein as an extended chain. This round only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be re-posted and LUA scripts and sharing will be allowed. You'll be able to load in your solutions from this puzzle and use scripting and sharing. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

Top groups


  1. Avatar for Crunching Family 23. Crunching Family 1 pt. 7,854
  2. Avatar for foldeRNA 24. foldeRNA 1 pt. 7,671
  3. Avatar for DSN @ Home 25. DSN @ Home 1 pt. 7,573
  4. Avatar for Deleted group 26. Deleted group pts. 7,506
  5. Avatar for uneRx 27. uneRx 1 pt. 3,799
  6. Avatar for test_group1 28. test_group1 1 pt. 0
  7. Avatar for Brony@Home 29. Brony@Home 1 pt. 0
  8. Avatar for :) 30. :) 1 pt. 0

  1. Avatar for piotrrieske 231. piotrrieske Lv 1 1 pt. 0
  2. Avatar for Vie 232. Vie Lv 1 1 pt. 0
  3. Avatar for terraner 233. terraner Lv 1 1 pt. 0
  4. Avatar for jflat06 234. jflat06 Lv 1 1 pt. 0
  5. Avatar for NickyCGS2 235. NickyCGS2 Lv 1 1 pt. 0
  6. Avatar for Pagdzin 236. Pagdzin Lv 1 1 pt. 0
  7. Avatar for fishercat 237. fishercat Lv 1 1 pt. 0
  8. Avatar for syoifczeri 238. syoifczeri Lv 1 1 pt. 0
  9. Avatar for bkoep 239. bkoep Lv 1 1 pt. 0
  10. Avatar for Grom 240. Grom Lv 1 1 pt. 0

Comments


bkoep Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Threonines at residues 20-22 are highly predicted to be part of a sheet. However, the Alanines at residues 94 and 96 are predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.