Placeholder image of a protein
Icon representing a puzzle

857: De-novo Freestyle 35: Hand-folding Round

Closed since almost 12 years ago

Intermediate Overall Prediction Hand-Folding

Summary


Created
March 11, 2014
Expires
Max points
100
Description

We are giving you another currently unsolved protein as an extended chain. This round only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be re-posted and LUA scripts and sharing will be allowed. You'll be able to load in your solutions from this puzzle and use scripting and sharing. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

Top groups


  1. Avatar for Go Science 11. Go Science 11 pts. 8,692
  2. Avatar for SETI.Germany 12. SETI.Germany 9 pts. 8,689
  3. Avatar for Deleted group 13. Deleted group pts. 8,682
  4. Avatar for Natural Abilities 14. Natural Abilities 5 pts. 8,662
  5. Avatar for Repro-men 15. Repro-men 4 pts. 8,606
  6. Avatar for Italiani Al Lavoro 16. Italiani Al Lavoro 3 pts. 8,504
  7. Avatar for Czech National Team 17. Czech National Team 2 pts. 8,371
  8. Avatar for FoldIt@Poland 20. FoldIt@Poland 1 pt. 8,298

  1. Avatar for allie_heather47 51. allie_heather47 Lv 1 29 pts. 8,712
  2. Avatar for Hiro Protagonist 52. Hiro Protagonist Lv 1 28 pts. 8,708
  3. Avatar for jobo0502 53. jobo0502 Lv 1 27 pts. 8,706
  4. Avatar for Anfinsen_slept_here 54. Anfinsen_slept_here Lv 1 27 pts. 8,704
  5. Avatar for petetrig 55. petetrig Lv 1 26 pts. 8,703
  6. Avatar for Deleted player 56. Deleted player 25 pts. 8,703
  7. Avatar for SKSbell 57. SKSbell Lv 1 24 pts. 8,695
  8. Avatar for davidgn 58. davidgn Lv 1 24 pts. 8,695
  9. Avatar for nicobul 59. nicobul Lv 1 23 pts. 8,694
  10. Avatar for Ch Garnier 60. Ch Garnier Lv 1 22 pts. 8,693

Comments


bkoep Staff Lv 1

Here are the secondary structure predictions!
Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Glutamates at residues 20 and 22 are highly predicted to be part of a sheet. However, the Glutamates at residues 33-34 are predicted to be in a helix!

The above predictions are already on the starting model (based on the horizontal lines in the above figure).


If you are a new Foldit player, please make sure you have completed all these tutorials before trying this puzzle:

  • lonely sheets,
  • lock and lower,
  • rebuild,
  • structure and rebuild,
  • control over clashing.